VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations

Stable Identifier
R-HSA-9668389
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, nuclear envelope
ReviewStatus
5/5
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VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations
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VPS4 binds the ESCRT-III complex assembled at nuclear envelope fenestrations, in part by binding CHMP2A (Vietri et al. 2015).
Literature References
PubMed ID Title Journal Year
26040712 Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing

Vietri, M, Schink, KO, Campsteijn, C, Wegner, CS, Schultz, SW, Christ, L, Thoresen, SB, Brech, A, Raiborg, C, Stenmark, H

Nature 2015
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Orthologous Events
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Bos taurus)
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Caenorhabditis elegans)
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Canis familiaris)
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Danio rerio)
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Dictyostelium discoideum)
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Drosophila melanogaster)
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Gallus gallus)
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Mus musculus)
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Rattus norvegicus)
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Saccharomyces cerevisiae)
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Schizosaccharomyces pombe)
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Sus scrofa)
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Xenopus tropicalis)
Authored
Gerace, L  (2019-11-07)
Created
Orlic-Milacic, M  (2019-11-25)
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