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p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:SHC1 [plasma membrane]
Stable Identifier
R-HSA-9665436
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by ERBB2 in Cancer (Homo sapiens)
Signaling by ERBB2 ECD mutants (Homo sapiens)
Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR bind SHC1 (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:SHC1 [plasma membrane] (Homo sapiens)
Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate SHC1 (Homo sapiens)
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:SHC1 [plasma membrane] (Homo sapiens)
Participants
components
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane]
(Homo sapiens)
SHC1 [cytosol]
(Homo sapiens)
Participates
as an output of
Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR bind SHC1 (Homo sapiens)
as an input of
Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate SHC1 (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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