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TWF2 [cytosol]
Stable Identifier
R-HSA-9663291
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Twinfilin-2, TWF2_HUMAN
Locations in the PathwayBrowser
Expand all
Sensory Perception (Homo sapiens)
Sensory processing of sound (Homo sapiens)
Sensory processing of sound by inner hair cells of the cochlea (Homo sapiens)
Mechanoelectrical transduction (MET) channel transports cations from the extracellular region into the cytosol of stereocilia of inner hair cell (Homo sapiens)
MET channel:Tip link:USH1C:USH1G:MYO7A:cytoskeleton (IHC) [plasma membrane] (Homo sapiens)
Inner hair cell stereocilium cytoskeleton [cytosol] (Homo sapiens)
Inner hair cell stereocilium tip [cytosol] (Homo sapiens)
TWF2 [cytosol] (Homo sapiens)
Sensory processing of sound by outer hair cells of the cochlea (Homo sapiens)
Mechanoelectrical transduction (MET) channel transports cations into the cytosol of stereocilia of cochlear outer hair cell (Homo sapiens)
MET channel:Tip link:USH1C:USH1G:MYO7A:cytoskeleton (OHC) [plasma membrane] (Homo sapiens)
Outer hair cell stereocilium cytoskeleton [cytosol] (Homo sapiens)
Outer hair cell stereocilium tip [cytosol] (Homo sapiens)
TWF2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6IBS0 TWF2
Gene Names
TWF2, PTK9L, MSTP011
Chain
initiator methionine:, chain:2-349
Reference Genes
BioGPS Gene:11344 TWF2
COSMIC (genes):TWF2 TWF2
CTD Gene:11344 TWF2
dbSNP Gene:11344 TWF2
ENSEMBL:ENSG00000247596 TWF2
HGNC:9621 TWF2
Monarch:11344 TWF2
NCBI Gene:11344 TWF2
OMIM:607433 TWF2
UCSC:Q6IBS0 TWF2
Reference Transcript
RefSeq:NM_007284.3 TWF2
Other Identifiers
11344
11756987_a_at
11756988_x_at
11757051_a_at
11757052_x_at
16954730
202009_PM_at
202009_at
2676010
2676011
2676012
2676013
2676014
2676015
2676016
2676017
2676018
2676019
2676020
2676021
2676022
2676023
2676024
2676025
2676026
2676030
2676031
2676032
35796_at
62800_at
8087860
A_23_P121265
GE56657
GO:0003723
GO:0003779
GO:0003785
GO:0005080
GO:0005515
GO:0005524
GO:0005546
GO:0005737
GO:0005856
GO:0005884
GO:0008092
GO:0008289
GO:0010591
GO:0010592
GO:0010976
GO:0030016
GO:0030027
GO:0030030
GO:0030042
GO:0030175
GO:0030426
GO:0030837
GO:0032420
GO:0032532
GO:0032956
GO:0042989
GO:0042995
GO:0043226
GO:0045296
GO:0045773
GO:0048471
GO:0051015
GO:0051016
GO:0070062
GO:0071300
GO:0071363
HMNXSV003021788
ILMN_1703305
PH_hs_0028432
TC03001448.hg
g6005845_3p_at
Participates
as a component of
Inner hair cell stereocilium tip [cytosol] (Homo sapiens)
Outer hair cell stereocilium tip [cytosol] (Homo sapiens)
Cross References
Guide to Pharmacology - Targets
2267
ENSEMBL
ENSP00000303908
,
ENST00000305533
OpenTargets
ENSG00000247596
HPA
ENSG00000247596-TWF2
PRO
Q6IBS0
Pharos - Targets
Q6IBS0
GlyGen
Q6IBS0
PDB
2VAC
,
2W0I
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P60709 ACTB
5
ACTB [plasma membrane]
(R-HSA-196016)
ACTB [lysosomal membrane]
(R-HSA-196160)
ACTB [cytosol]
(R-HSA-201861)
ACTB [nucleoplasm]
(R-HSA-3321990)
Unfolded ACTB [cytosol]
(R-HSA-390462)
0.643
4
UniProt:P47756 CAPZB
1
CAPZB [cytosol]
(R-HSA-879409)
0.564
2
UniProt:P62736 ACTA2
1
ACTA2 [cytosol]
(R-HSA-445792)
0.527
3
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