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EPS8L2 [cytosol]
Stable Identifier
R-HSA-9663247
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Epidermal growth factor receptor kinase substrate 8-like protein 2, ES8L2_HUMAN
Locations in the PathwayBrowser
Expand all
Sensory Perception (Homo sapiens)
Sensory processing of sound (Homo sapiens)
Sensory processing of sound by inner hair cells of the cochlea (Homo sapiens)
Mechanoelectrical transduction (MET) channel transports cations from the extracellular region into the cytosol of stereocilia of inner hair cell (Homo sapiens)
MET channel:Tip link:USH1C:USH1G:MYO7A:cytoskeleton (IHC) [plasma membrane] (Homo sapiens)
Inner hair cell stereocilium cytoskeleton [cytosol] (Homo sapiens)
Inner hair cell stereocilium tip [cytosol] (Homo sapiens)
EPS8L2 [cytosol] (Homo sapiens)
Sensory processing of sound by outer hair cells of the cochlea (Homo sapiens)
Mechanoelectrical transduction (MET) channel transports cations into the cytosol of stereocilia of cochlear outer hair cell (Homo sapiens)
MET channel:Tip link:USH1C:USH1G:MYO7A:cytoskeleton (OHC) [plasma membrane] (Homo sapiens)
Outer hair cell stereocilium cytoskeleton [cytosol] (Homo sapiens)
Outer hair cell stereocilium tip [cytosol] (Homo sapiens)
EPS8L2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H6S3 EPS8L2
Gene Names
EPS8L2, EPS8R2, PP13181
Chain
chain:1-715
Reference Genes
BioGPS Gene:64787 EPS8L2
COSMIC (genes):EPS8L2 EPS8L2
CTD Gene:64787 EPS8L2
dbSNP Gene:64787 EPS8L2
ENSEMBL:ENSG00000177106 EPS8L2
ENSEMBL_homo_sapiens_GENE:ENSG00000177106.17 EPS8L2
HGNC:21296 EPS8L2
KEGG Gene (Homo sapiens):64787 EPS8L2
Monarch:64787 EPS8L2
NCBI Gene:64787 EPS8L2
OMIM:614988 EPS8L2
UCSC:Q9H6S3 EPS8L2
Reference Transcript
RefSeq:XM_017018132.1 EPS8L2
RefSeq:NM_022772.3 EPS8L2
RefSeq:XM_017018130.1 EPS8L2
RefSeq:XM_017018131.1 EPS8L2
Other Identifiers
11716776_a_at
11716777_s_at
11754611_a_at
11760459_x_at
16720268
218180_PM_s_at
218180_s_at
222546_PM_s_at
222546_s_at
3316150
3316151
3316152
3316155
3316156
3316157
3316160
3316161
3316162
3316163
3316164
3316165
3316166
3316168
3316170
3316172
3316175
3316178
3316183
3316184
3316185
3316187
3316189
3316190
3316191
3316192
3316193
3316194
3316195
3316197
46095_at
46096_g_at
60445_at
64787
75434_at
7937443
A_23_P147822
GE82721
GO:0003779
GO:0005085
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0005886
GO:0007266
GO:0007605
GO:0008092
GO:0023052
GO:0031982
GO:0032420
GO:0032421
GO:0032426
GO:0032587
GO:0032991
GO:0035023
GO:0042995
GO:0043226
GO:0045296
GO:0050877
GO:0070062
GO:0098772
GO:1900029
HMNXSV003041523
HMNXSV003052635
Hs.55016.0.S1_3p_a_at
ILMN_1780827
PH_hs_0027656
TC11000026.hg
g12232452_3p_a_at
Participates
as a component of
Inner hair cell stereocilium tip [cytosol] (Homo sapiens)
Outer hair cell stereocilium tip [cytosol] (Homo sapiens)
Cross References
RefSeq
XP_016873619.1
,
NP_073609.2
,
XP_016873620.1
,
XP_016873621.1
OpenTargets
ENSG00000177106
HPA
ENSG00000177106-EPS8L2
GeneCards
Q9H6S3
Ensembl
ENSP00000436035
,
ENST00000533256
,
ENSP00000435585
,
ENSP00000480201
,
ENST00000530636
,
ENSG00000177106
,
ENSP00000436230
,
ENST00000526198
,
ENST00000318562
,
ENST00000614442
,
ENSP00000320828
PRO
Q9H6S3
Pharos - Targets
Q9H6S3
PDB
1WXB
,
1WWU
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:P07196 NEFL
1
NEFL [cytosol]
(R-HSA-432284)
0.556
3
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