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PLS1 [cytosol]
Stable Identifier
R-HSA-9662403
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Plastin-1, PLSI_HUMAN
Locations in the PathwayBrowser
Expand all
Sensory Perception (Homo sapiens)
Sensory processing of sound (Homo sapiens)
Sensory processing of sound by inner hair cells of the cochlea (Homo sapiens)
Mechanoelectrical transduction (MET) channel transports cations from the extracellular region into the cytosol of stereocilia of inner hair cell (Homo sapiens)
MET channel:Tip link:USH1C:USH1G:MYO7A:cytoskeleton (IHC) [plasma membrane] (Homo sapiens)
Inner hair cell stereocilium cytoskeleton [cytosol] (Homo sapiens)
Stereocilium shaft [cytosol] (Homo sapiens)
PLS1 [cytosol] (Homo sapiens)
Sensory processing of sound by outer hair cells of the cochlea (Homo sapiens)
Mechanoelectrical transduction (MET) channel transports cations into the cytosol of stereocilia of cochlear outer hair cell (Homo sapiens)
MET channel:Tip link:USH1C:USH1G:MYO7A:cytoskeleton (OHC) [plasma membrane] (Homo sapiens)
Outer hair cell stereocilium cytoskeleton [cytosol] (Homo sapiens)
Stereocilium shaft [cytosol] (Homo sapiens)
PLS1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q14651 PLS1
Gene Names
PLS1
Chain
chain:1-629
Reference Genes
BioGPS Gene:5357 PLS1
COSMIC (genes):PLS1 PLS1
CTD Gene:5357 PLS1
dbSNP Gene:5357 PLS1
ENSEMBL:ENSG00000120756 PLS1
HGNC:9090 PLS1
Monarch:5357 PLS1
NCBI Gene:5357 PLS1
OMIM:602734 PLS1
UCSC:Q14651 PLS1
Reference Transcript
RefSeq:XM_011512901.1 PLS1
RefSeq:NM_001145319.1 PLS1
RefSeq:XM_011512903.2 PLS1
RefSeq:NM_001172312.1 PLS1
RefSeq:XM_017006627.1 PLS1
RefSeq:XM_006713660.3 PLS1
RefSeq:NM_002670.2 PLS1
RefSeq:XM_011512900.2 PLS1
RefSeq:XM_017006626.1 PLS1
Other Identifiers
11726470_s_at
11741044_a_at
16946485
205190_PM_at
205190_at
2645907
2645911
2645915
2645919
2645920
2645921
2645927
2645928
2645930
2645931
2645933
2645934
2645935
2645936
2645937
2645939
2645943
2645944
2645945
2645946
2645947
2645948
2645949
2645950
3388508
39951_at
5357
8083146
89060_at
A_14_P119901
A_23_P211909
GE57667
GO:0001951
GO:0003779
GO:0005198
GO:0005200
GO:0005509
GO:0005515
GO:0005737
GO:0005829
GO:0005856
GO:0005884
GO:0005886
GO:0005903
GO:0007010
GO:0008092
GO:0008597
GO:0022600
GO:0032420
GO:0032432
GO:0032532
GO:0040018
GO:0042995
GO:0043226
GO:0046872
GO:0051015
GO:0051017
GO:0051639
GO:0060088
GO:0060121
GO:0070062
GO:0098772
GO:1902896
GO:1903078
GO:1990357
HMNXSV003028519
ILMN_1759206
ILMN_2074044
L20826_at
PH_hs_0023023
TC03000768.hg
g4505896_3p_at
Participates
as a component of
Stereocilium shaft [cytosol] (Homo sapiens)
Cross References
ENSEMBL
ENST00000457734
,
ENST00000337777
,
ENST00000497002
,
ENSP00000336831
,
ENSP00000387890
,
ENSP00000418700
OpenTargets
ENSG00000120756
HPA
ENSG00000120756-PLS1
PRO
Q14651
Pharos - Targets
Q14651
GlyGen
Q14651
Orphanet
PLS1
HMDB Protein
HMDBP07946
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9UKA8 RCAN3
1
RCAN3 [cytosol]
(R-HSA-9728800)
0.527
2
UniProt:P13796 LCP1
1
LCP1 [cell junction]
(R-HSA-8950517)
0.527
2
UniProt:Q8WVK2 SNRNP27
1
SNRNP27 [nucleoplasm]
(R-HSA-6806778)
0.527
2
UniProt:P25963 NFKBIA
9
NFKBIA [cytosol]
(R-HSA-168151)
p-S32,S36-NFKBIA [cytosol]
(R-HSA-177677)
Ub-K21,22-p-S32,S36-NFKBIA [cytosol]
(R-HSA-1168581)
NFKBIA [nucleoplasm]
(R-HSA-4656929)
monoSUMO1-K21-NFKBIA [nucleoplasm]
(R-HSA-4656935)
NFKBIA S32I [cytosol]
(R-HSA-5228846)
NFKBIA F2_M37del [cytosol]
(R-HSA-9630119)
NFKBIA M37K [cytosol]
(R-HSA-5228805)
PolyUb-NFKBIA [cytosol]
(R-HSA-6782960)
0.527
2
UniProt:Q9H2D1 SLC25A32
1
SLC25A32 [mitochondrial inner membrane]
(R-HSA-200645)
0.527
2
UniProt:Q9UIM3 FKBPL
1
FKBPL [cytosol]
(R-HSA-8852374)
0.527
2
UniProt:P24387 CRHBP
1
CRHBP [extracellular region]
(R-HSA-8937598)
0.527
2
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