Reactome | RGL3 [cytosol]

RGL3 [cytosol]

Stable Identifier

R-HSA-9660475

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ral guanine nucleotide dissociation stimulator-like 3, RGL3_HUMAN

Locations in the PathwayBrowser

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Immune System (Homo sapiens)

- Cytokine Signaling in Immune system (Homo sapiens)
  - FLT3 Signaling (Homo sapiens)
    - RAF/MAP kinase cascade (Homo sapiens)
      - RAS:GTP binds RAL GDS proteins (Homo sapiens)
        
        RAL GDS proteins [cytosol] (Homo sapiens)
        
        RGL3 [cytosol] (Homo sapiens)
        
        S-Farn-Me_2xPalmS HRAS:GTP:RAL GDS proteins [plasma membrane] (Homo sapiens)
        
        RAL GDS proteins [cytosol] (Homo sapiens)
        
        RGL3 [cytosol] (Homo sapiens)

Signal Transduction (Homo sapiens)

- MAPK family signaling cascades (Homo sapiens)
  - MAPK1/MAPK3 signaling (Homo sapiens)
    - RAF/MAP kinase cascade (Homo sapiens)
      - RAS:GTP binds RAL GDS proteins (Homo sapiens)
        
        RAL GDS proteins [cytosol] (Homo sapiens)
        
        RGL3 [cytosol] (Homo sapiens)
        
        S-Farn-Me_2xPalmS HRAS:GTP:RAL GDS proteins [plasma membrane] (Homo sapiens)
        
        RAL GDS proteins [cytosol] (Homo sapiens)
        
        RGL3 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q3MIN7 RGL3

Gene Names

RGL3

Chain

chain:1-710

Reference Genes

BioGPS Gene:57139 RGL3

COSMIC (genes):RGL3 RGL3

CTD Gene:57139 RGL3

dbSNP Gene:57139 RGL3

ENSEMBL:ENSG00000205517 RGL3

HGNC:30282 RGL3

KEGG Gene (Homo sapiens):57139 RGL3

Monarch:57139 RGL3

NCBI Gene:57139 RGL3

OMIM:616743 RGL3

UCSC:Q3MIN7 RGL3

Reference Transcript

Other Identifiers

11742849_a_at

11749274_a_at

11761292_x_at

16868940

228877_at

3850886

3850892

3850893

3850894

3850898

3850899

3850900

3850901

3850903

3850905

3850907

3850908

3850909

3850910

3850912

3850914

3850915

3850917

3850920

3850923

3850925

3850927

3850928

47475_at

57139

8034227

A_33_P3293213

A_33_P3356392

GE80490

GO:0003674

GO:0005085

GO:0007165

GO:0007264

GO:0008150

GO:0008321

GO:0017016

GO:0019899

GO:0031267

GO:0043547

Hs.127826.0.A1_3p_at

TC19002677.hg

Participant Of

hasMember

RAL GDS proteins [cytosol]

Inferred To

gefS [cytosol] (Dictyostelium discoideum)

gefC [cytosol] (Dictyostelium discoideum)

ste6 [cytosol] (Schizosaccharomyces pombe)

efc25 [cytosol] (Schizosaccharomyces pombe)

RGL3 [cytosol] (Bos taurus)

RGL3 [cytosol] (Canis familiaris)

RGL3 [cytosol] (Dictyostelium discoideum)

rgl-1 [cytosol] (Caenorhabditis elegans)

gefW [cytosol] (Dictyostelium discoideum)

gefD [cytosol] (Dictyostelium discoideum)

gefM [cytosol] (Dictyostelium discoideum)

BUD5 [cytosol] (Saccharomyces cerevisiae)

rgl3 [cytosol] (Xenopus tropicalis)

gefK [cytosol] (Dictyostelium discoideum)

gefB [cytosol] (Dictyostelium discoideum)

CDC25 [cytosol] (Saccharomyces cerevisiae)

Rgl [cytosol] (Drosophila melanogaster)

gefY [cytosol] (Dictyostelium discoideum)

gflB [cytosol] (Dictyostelium discoideum)

rgl3a [cytosol] (Danio rerio)

gefN [cytosol] (Dictyostelium discoideum)

gefE [cytosol] (Dictyostelium discoideum)

Homologues of RGL3 [cytosol] (Dictyostelium discoideum)

Homologues of RGL3 [cytosol] (Saccharomyces cerevisiae)

Homologues of RGL3 [cytosol] (Schizosaccharomyces pombe)

gefO [cytosol] (Dictyostelium discoideum)

gefG [cytosol] (Dictyostelium discoideum)

Rgl3 [cytosol] (Mus musculus)

Rgl3 [cytosol] (Rattus norvegicus)

gefL [cytosol] (Dictyostelium discoideum)

gefQ [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_001030300.3, NP_001155088.2

OpenTargets

ENSG00000205517

HPA

ENSG00000205517-RGL3

GeneCards

Q3MIN7

Ensembl

ENSP00000377075, ENST00000393423, ENSG00000205517

PRO

Q3MIN7

HMDB Protein

HMDBP08544

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