EML4, a microtubule binding protein involved in mitotic spindle formation, forms homotrimers. Trimerization involves the trimerization domain (TD) and the basic region of EML4 and is necessary for its association with the microtubules (Richards et al. 2015). Heterotrimerization of EML4 with other EML family members has not been examined.
O'Regan, L, Richards, MW, Bayliss, R, Fry, AM, Straube, A, Montgomery, JM, Roth, D
© 2023 Reactome