FOXO1,FOXO3 and SMAD3 bind TRIM63 gene promoter

Stable Identifier
R-HSA-9625749
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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FOXO1 and FOXO3 can bind to the promoter of the TRIM63 gene, encoding an E3 ubiquitin ligase MURF1, together with SMAD3 (Bollinger et al. 2014, Wang et al. 2017). SMAD3 in the nucleus exist as a heterotrimer composed of two molecules of SMAD2 or SMAD3 and one molecule of SMAD4.

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