CCNG2 gene expression is stimulated by FOXO1,FOXO3,(FOXO4)

Stable Identifier
R-HSA-9620837
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
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CCNG2 gene expression is stimulated by FOXO1,FOXO3,(FOXO4)
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FOXO1, FOXO3 and probably FOXO4 directly stimulate transcription of the CCNG2 gene, encoding a cell cycle inhibitor Cyclin-G2 (Martinez-Gac et al. 2004, Chen et al. 2006). FOXO4 stimulates CCNG2 transcription, but direct binding of FOXO4 to the CCNG2 gene promoter has not been demonstrated (Martinez-Gac et al. 2004).
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Output
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This event is regulated
Positively by
Regulator
FOXO1,FOXO3,(FOXO4):CCNG2 gene [nucleoplasm] (Homo sapiens)
Active Unit
FOXO1,FOXO3,(FOXO4) [nucleoplasm]
Inferred From
Ccng2 gene expression is stimulated by FOXO1,FOXO3 (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-10-11)
Reviewed
Bertaggia, E  (2018-10-26)
Donlon, T  (2018-10-17)
Created
Orlic-Milacic, M  (2018-09-25)
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