ACEIs translocate from ER lumen to extracellular region

Stable Identifier
R-HSA-9619034
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen, extracellular region
ReviewStatus
5/5
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ACEIs translocate from ER lumen to extracellular region
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To exert their biological effects on extracellular angiotensin, angiotensin-converting enzyme inhibitors (ACEIs) translocate to the extracellular region by an unknown mechanism (Johnston et al. 1986).
Literature References
PubMed ID Title Journal Year
2422495 Evaluation of angiotensin converting enzyme (ACE) in the pharmacokinetics and pharmacodynamics of ACE inhibitors

Jackson, B, Cubela, R, Arnolda, L, Larmour, I, Johnston, CI

J. Cardiovasc. Pharmacol. 1986
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Authored
Jassal, B  (2018-09-14)
Reviewed
Toomey, JR  (2018-09-14)
Created
Jassal, B  (2018-09-14)
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