ERBB4s80:ESR1 binds ERBB4 gene promoter

Stable Identifier
R-HSA-9612672
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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The complex of intracellular ERBB4 fragment, ERBB4s80 (E4ICD), and activated estrogen receptor (ESR1:estrogen), binds to estrogen-response elements in the promoter of the ERBB4 gene (Zhu et al. 2006).
Literature References
PubMed ID Title Journal Year
16912174 Coregulation of estrogen receptor by ERBB4/HER4 establishes a growth-promoting autocrine signal in breast tumor cells

Nair, SS, Vadlamudi, RK, Marrero, L, Zhu, Y, Jones, FE, Williams, CC, Pandey, AK, Sullivan, LL

Cancer Res 2006
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