SPARC gene transcription is stimulated by ERBB4s80

Stable Identifier
R-HSA-9612277
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, plasma membrane
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
SPARC gene transcription is stimulated by ERBB4s80
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The intracellular fragment of ERBB4, ERBB4s80 (E4ICD) stimulates transcription of the SPARC gene, encoding Basement-membrane protein 40 (BM-40) (Wali et al. 2014).

Literature References
PubMed ID Title Journal Year
24829397 Convergent and divergent cellular responses by ErbB4 isoforms in mammary epithelial cells

Wali, VB, Haskins, JW, Gilmore-Hebert, M, Platt, JT, Liu, Z, Stern, DF

Mol. Cancer Res. 2014
Participants
Input
Output
Participant Of
hasEvent
This event is regulated
Positively by
Authored
Orlic-Milacic, M  (2018-06-28)
Stern, DF  (2019-02-21)
Created
Orlic-Milacic, M  (2018-06-28)