ADAP1 gene expression is inhibited by ERBB4s80

Stable Identifier
R-HSA-9612257
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
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ADAP1 gene expression is inhibited by ERBB4s80
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The intracellular fragment of ERBB4, ERBB4s80 (E4ICD) inhibits transcription of the ADAP1 gene, encoding Arf-GAP with dual PH domain-containing protein 1 (also known as CENTA1 or Centaurin-alpha-1).

Literature References
PubMed ID Title Journal Year
24829397 Convergent and divergent cellular responses by ErbB4 isoforms in mammary epithelial cells

Liu, Z, Gilmore-Hebert, M, Stern, DF, Wali, VB, Platt, JT, Haskins, JW

Mol. Cancer Res. 2014
Participants
Input
Output
Participates
as an event of
This event is regulated
Negatively by
Regulator
ERBB4s80:ADAP1 gene [nucleoplasm] (Homo sapiens)
Active Unit
ERBB4s80 [nucleoplasm]
Authored
Stern, DF  (2019-02-21)
Orlic-Milacic, M  (2018-06-28)
Created
Orlic-Milacic, M  (2018-06-27)
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