APOE gene transcription is stimulated by ERBB4s80

Stable Identifier
R-HSA-9612243
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, extracellular region
ReviewStatus
5/5
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APOE gene transcription is stimulated by ERBB4s80
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Transcription of the APOE gene, encoding Apolipoprotein E, involved in binding and internalization of lipoprotein particles, is stimulated by the intracellular fragment of ERBB4, ERBB4s80 (E4ICD) (Wali et al. 2014).
Literature References
PubMed ID Title Journal Year
24829397 Convergent and divergent cellular responses by ErbB4 isoforms in mammary epithelial cells

Liu, Z, Gilmore-Hebert, M, Stern, DF, Wali, VB, Platt, JT, Haskins, JW

Mol. Cancer Res. 2014
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Output
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as an event of
This event is regulated
Positively by
Regulator
ERBB4s80:APOE gene [nucleoplasm] (Homo sapiens)
Active Unit
ERBB4s80 [nucleoplasm]
Authored
Stern, DF  (2019-02-21)
Orlic-Milacic, M  (2018-06-28)
Created
Orlic-Milacic, M  (2018-06-27)
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