| 20418187 |
Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis
D'Agostino, VG,
Minoprio, A,
Torreri, P,
Marinoni, I,
Bossa, C,
Petrucci, TC,
Albertini, AM,
Ranzani, GN,
Bignami, M,
Mazzei, F
|
DNA Repair (Amst.) |
2010 |
| 15987719 |
Cells with pathogenic biallelic mutations in the human MUTYH gene are defective in DNA damage binding and repair
Parker, AR,
Sieber, OM,
Shi, C,
Hua, L,
Takao, M,
Tomlinson, IP,
Eshleman, JR
|
Carcinogenesis |
2005 |
| 18534194 |
Characterization of mutant MUTYH proteins associated with familial colorectal cancer
Ali, M,
Kim, H,
Cleary, S,
Cupples, C,
Gallinger, S,
Bristow, R
|
Gastroenterology |
2008 |
| 12628248 |
Insight into the functional consequences of inherited variants of the hMYH adenine glycosylase associated with colorectal cancer: complementation assays with hMYH variants and pre-steady-state kinetics of the corresponding mutated E.coli enzymes
Chmiel, NH,
Livingston, AL,
David, SS
|
J. Mol. Biol. |
2003 |
| 19953527 |
MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay
Molatore, S,
Russo, MT,
D'Agostino, VG,
Barone, F,
Matsumoto, Y,
Albertini, AM,
Minoprio, A,
Degan, P,
Mazzei, F,
Bignami, M,
Ranzani, GN
|
Hum. Mutat. |
2010 |
| 16134146 |
A novel functionally deficient MYH variant in individuals with colorectal adenomatous polyposis
Alhopuro, P,
Parker, AR,
Lehtonen, R,
Enholm, S,
Järvinen, HJ,
Mecklin, JP,
Karhu, A,
Eshleman, JR,
Aaltonen, LA
|
Hum. Mutat. |
2005 |
| 19443904 |
Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma
Forsbring, M,
Vik, ES,
Dalhus, B,
Karlsen, TH,
Bergquist, A,
Schrumpf, E,
Bjørås, M,
Boberg, KM,
Alseth, I
|
Carcinogenesis |
2009 |
| 15673720 |
Functional characterization of two human MutY homolog (hMYH) missense mutations (R227W and V232F) that lie within the putative hMSH6 binding domain and are associated with hMYH polyposis
Bai, H,
Jones, S,
Guan, X,
Wilson, TM,
Sampson, JR,
Cheadle, JP,
Lu, AL
|
Nucleic Acids Res. |
2005 |
| 18422726 |
Genomic and functional analyses of MUTYH in Japanese patients with adenomatous polyposis
Yanaru-Fujisawa, R,
Matsumoto, T,
Ushijima, Y,
Esaki, M,
Hirahashi, M,
Gushima, M,
Yao, T,
Nakabeppu, Y,
Iida, M
|
Clin. Genet. |
2008 |
| 12393807 |
Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C-->T:A mutations
Jones, S,
Emmerson, P,
Maynard, J,
Best, JM,
Jordan, S,
Williams, GT,
Sampson, JR,
Cheadle, JP
|
Hum. Mol. Genet. |
2002 |
| 20848659 |
Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer
Goto, M,
Shinmura, K,
Nakabeppu, Y,
Tao, H,
Yamada, H,
Tsuneyoshi, T,
Sugimura, H
|
Hum. Mutat. |
2010 |
| 23322991 |
Impaired suppressive activities of human MUTYH variant proteins against oxidative mutagenesis
Shinmura, K,
Goto, M,
Tao, H,
Matsuura, S,
Matsuda, T,
Sugimura, H
|
World J. Gastroenterol. |
2012 |
| 22926731 |
Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells
Raetz, AG,
Xie, Y,
Kundu, S,
Brinkmeyer, MK,
Chang, C,
David, SS
|
Carcinogenesis |
2012 |
| 17081686 |
Functional characterization of human MutY homolog (hMYH) missense mutation (R231L) that is linked with hMYH-associated polyposis
Bai, H,
Grist, S,
Gardner, J,
Suthers, G,
Wilson, TM,
Lu, AL
|
Cancer Lett. |
2007 |
| 19836313 |
Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer
Kundu, S,
Brinkmeyer, MK,
Livingston, AL,
David, SS
|
DNA Repair (Amst.) |
2009 |
| 15036665 |
Identification of critical residues required for the mutation avoidance function of human MutY (hMYH) and implications in colorectal cancer
Wooden, SH,
Bassett, HM,
Wood, TG,
McCullough, AK
|
Cancer Lett. |
2004 |