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UBE2G2 [cytosol]
Stable Identifier
R-HSA-947640
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ubiquitin-conjugating enzyme E2 G2, UB2G2_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2G2 [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2G2 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2G2 [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2G2 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2G2 [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2G2 [cytosol] (Homo sapiens)
Transfer of ubiquitin from E1 to E2 (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2G2 [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2G2 [cytosol] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Protein ubiquitination (Homo sapiens)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Homo sapiens)
UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Homo sapiens)
E2 ubiquitin conjugating enzyme (UBA1 substrate) [cytosol] (Homo sapiens)
UBE2G2 [cytosol] (Homo sapiens)
UBA6 conjugates ubiquitin to cytosolic E2 enzymes (Homo sapiens)
E2 ubiquitin conjugating enzyme (UBA6 substrate) [cytosol] (Homo sapiens)
UBE2G2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P60604 UBE2G2
Gene Names
UBE2G2, UBC7
Chain
initiator methionine:, chain:2-165
Reference Genes
BioGPS Gene:7327 UBE2G2
COSMIC (genes):UBE2G2 UBE2G2
CTD Gene:7327 UBE2G2
dbSNP Gene:7327 UBE2G2
ENSEMBL:ENSG00000184787 UBE2G2
ENSEMBL_homo_sapiens_GENE:ENSG00000184787.19 UBE2G2
HGNC:12483 UBE2G2
KEGG Gene (Homo sapiens):7327 UBE2G2
Monarch:7327 UBE2G2
NCBI Gene:7327 UBE2G2
OMIM:603124 UBE2G2
UCSC:P60604 UBE2G2
Reference Transcript
RefSeq:XM_017028469.1 UBE2G2
RefSeq:NM_001202489.1 UBE2G2
RefSeq:NM_003343.5 UBE2G2
RefSeq:NM_182688.2 UBE2G2
Other Identifiers
11731419_x_at
11731420_x_at
11731421_a_at
11759057_at
1557053_PM_s_at
1557053_s_at
209041_PM_s_at
209041_s_at
209042_3p_s_at
209042_PM_s_at
209042_s_at
32236_at
3934653
3934654
3934655
3934656
3934660
3934661
3934662
3934665
3934667
3934668
7327
8070799
A_23_P211179
A_24_P357037
GE62723
GO:0000166
GO:0003824
GO:0004842
GO:0005515
GO:0005524
GO:0005783
GO:0005811
GO:0005829
GO:0006511
GO:0006886
GO:0016567
GO:0016740
GO:0019787
GO:0030163
GO:0030433
GO:0032446
GO:0035458
GO:0036211
GO:0042802
GO:0043226
GO:0061631
GO:0070936
GO:0140096
GO:1904153
HMNXSV003011740
Hs.192853.0.A1_3p_a_at
ILMN_1785179
ILMN_2297824
PH_hs_0023233
g12804628_3p_x_at
Participates
as a member of
E2 ubiquitin conjugating enzyme (UBA6 substrate) [cytosol] (Homo sapiens)
E2 ubiquitin conjugating enzyme (UBA1 substrate) [cytosol] (Homo sapiens)
as a candidate of
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
Other forms of this molecule
Ub-C89-UBE2G2 [cytosol]
Inferred To
UBC7 [cytosol]
(Saccharomyces cerevisiae)
UBE2G2 [cytosol]
(Bos taurus)
UBE2G2 [cytosol]
(Canis familiaris)
UBE2G2 [cytosol]
(Dictyostelium discoideum)
UBE2G2 [cytosol]
(Gallus gallus)
UBE2G2 [cytosol]
(Sus scrofa)
Ubc7 [cytosol]
(Drosophila melanogaster)
ubc-14 [cytosol]
(Caenorhabditis elegans)
Ube2g2 [cytosol]
(Mus musculus)
Ube2g2 [cytosol]
(Rattus norvegicus)
ubc7 [cytosol]
(Schizosaccharomyces pombe)
ube2g2 [cytosol]
(Danio rerio)
ube2g2 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_003334.2
,
NP_001189418.1
,
XP_016883958.1
,
NP_872630.1
OpenTargets
ENSG00000184787
GeneCards
P60604
HPA
ENSG00000184787-UBE2G2
Ensembl
ENST00000345496
,
ENSG00000184787
,
ENSP00000338348
,
ENST00000330942
,
ENSP00000331384
PRO
P60604
Pharos - Targets
P60604
HMDB Protein
HMDBP11989
PDB
7LEW
,
2CYX
,
3H8K
,
2LXP
,
2KLY
,
4LAD
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P0CG48 UBC
20
UBC(381-456) [endocytic vesicle membrane]
(R-HSA-939218)
UBC(533-608) [endocytic vesicle membrane]
(R-HSA-939220)
UBC(609-684) [endocytic vesicle membrane]
(R-HSA-939223)
UBC(457-532) [endocytic vesicle membrane]
(R-HSA-939195)
UBC(153-228) [endocytic vesicle membrane]
(R-HSA-939194)
UBC(305-380) [endocytic vesicle membrane]
(R-HSA-939228)
UBC(229-304) [endocytic vesicle membrane]
(R-HSA-939177)
UBC(77-152) [endocytic vesicle membrane]
(R-HSA-939210)
UBC(1-76) [endocytic vesicle membrane]
(R-HSA-939245)
Ub-565-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783166)
Ub-337-UBC(305-380) [mitochondrial outer membrane]
(R-HSA-6783121)
Ub-185-UBC(153-228) [mitochondrial outer membrane]
(R-HSA-6783154)
Ub-261-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783028)
Ub-413-UBC(381-456) [mitochondrial outer membrane]
(R-HSA-6783061)
Ub-109-UBC(77-152) [mitochondrial outer membrane]
(R-HSA-6783158)
Ub-641-UBC(609-684) [mitochondrial outer membrane]
(R-HSA-6783182)
Ub-33-UBC(1-76) [mitochondrial outer membrane]
(R-HSA-6783073)
Ub-489-UBC(457-532) [mitochondrial outer membrane]
(R-HSA-6783078)
Ub-291-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783193)
Ub-595-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783130)
0.556
3
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