Reactome | CysS452-MOCS3 [cytosol]

CysS452-MOCS3 [cytosol]

Stable Identifier

R-HSA-947553

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

MOCS3-S-S(1-)

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O95396 MOCS3

Gene Names

MOCS3, UBA4

Chain

chain:1-460

Reference Genes

BioGPS Gene:27304 MOCS3

COSMIC (genes):MOCS3 MOCS3

CTD Gene:27304 MOCS3

dbSNP Gene:27304 MOCS3

ENSEMBL:ENSG00000124217 MOCS3

HGNC:15765 MOCS3

KEGG:hsa:27304 MOCS3

Monarch:27304 MOCS3

NCBI Gene:27304 MOCS3

OMIM:609277 MOCS3

UCSC:O95396 MOCS3

Reference Transcript

RefSeq:NM_014484.4 MOCS3

Other Identifiers

11739791_at

11739792_at

16914888

206141_PM_at

206141_at

27304

3539268

35399_at

3888951

3888952

3888953

3888955

3888956

46987_i_at

46988_r_at

8063427

A_14_P133687

A_23_P28811

A_33_P3350202

GE54797

GO:0002098

GO:0002143

GO:0003824

GO:0004792

GO:0005515

GO:0005524

GO:0005737

GO:0005829

GO:0006399

GO:0006777

GO:0008033

GO:0008641

GO:0016740

GO:0016779

GO:0016783

GO:0016874

GO:0032447

GO:0034227

GO:0042292

GO:0043545

GO:0046872

GO:0061604

GO:0061605

GO:0070566

GO:0140096

GO:0140657

HMNXSV003030129

ILMN_1766652

PH_hs_0014227

PH_hs_0029272

PH_hs_0031918

TC20000410.hg

g7657338_3p_at

Participates

as a component of

MOCS3-S-S(1-):Zn2+ [cytosol] (Homo sapiens)

Other forms of this molecule

MOCS3 [cytosol]

Inferred To

CysS452-MOCS3 [cytosol] (Bos taurus)

CysS452-MOCS3 [cytosol] (Caenorhabditis elegans)

CysS452-MOCS3 [cytosol] (Canis familiaris)

CysS452-MOCS3 [cytosol] (Danio rerio)

CysS452-MOCS3 [cytosol] (Dictyostelium discoideum)

CysS452-MOCS3 [cytosol] (Drosophila melanogaster)

CysS452-MOCS3 [cytosol] (Gallus gallus)

CysS452-MOCS3 [cytosol] (Mus musculus)

CysS452-MOCS3 [cytosol] (Plasmodium falciparum)

CysS452-MOCS3 [cytosol] (Rattus norvegicus)

CysS452-MOCS3 [cytosol] (Saccharomyces cerevisiae)

CysS452-MOCS3 [cytosol] (Schizosaccharomyces pombe)

CysS452-MOCS3 [cytosol] (Sus scrofa)

CysS452-MOCS3 [cytosol] (Xenopus tropicalis)

Modified Residues

Name

L-cysteine persulfide at 412

Coordinate

412

PsiMod Name

L-cysteine persulfide

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to L-cysteine persulfide.

Cross References

ENSEMBL

ENST00000244051, ENSP00000244051, ENSG00000124217

OpenTargets

ENSG00000124217

IntEnz

2.7.7.80, 2.8.1.11

GeneCards

MOCS3

HPA

ENSG00000124217-MOCS3

PRO

O95396

Pharos - Targets

O95396

HMDB Protein

HMDBP02017

PDB

3I2V

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95076 ALX3	1	ALX3 [nucleoplasm] (R-HSA-9858233)	0.527	2
UniProt:Q9H5K3 POMK	1	POMK [endoplasmic reticulum membrane] (R-HSA-8879120)	0.527	2