Reactome | ENTPD1 [plasma membrane]

ENTPD1 [plasma membrane]

Stable Identifier

R-HSA-913566

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Ectonucleoside triphosphate diphosphohydrolase 1, Ecto-ADPase 1, ENTP1_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Parasitic Infection Pathways (Homo sapiens)
    - Leishmania infection (Homo sapiens)
      - Cell recruitment (pro-inflammatory response) (Homo sapiens)
        
        Purinergic signaling in leishmaniasis infection (Homo sapiens)
        
        NTPDase1 hydrolyzes nucleoside triphosphates (Homo sapiens)
        
        NTPDase1:Ca2+,Mg2+ [plasma membrane] (Homo sapiens)
        
        NTPDase1 [plasma membrane] (Homo sapiens)
        
        ENTPD1 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P49961 ENTPD1

Gene Names

ENTPD1, CD39

Chain

chain:1-510

Reference Genes

BioGPS Gene:953 ENTPD1

COSMIC (genes):ENTPD1 ENTPD1

CTD Gene:953 ENTPD1

dbSNP Gene:953 ENTPD1

ENSEMBL:ENSG00000138185 ENTPD1

HGNC:3363 ENTPD1

KEGG:hsa:953 ENTPD1

Monarch:953 ENTPD1

NCBI Gene:953 ENTPD1

OMIM:601752 ENTPD1

UCSC:P49961 ENTPD1

Reference Transcript

Other Identifiers

11724006_a_at

11724007_s_at

11724008_a_at

11749188_a_at

16707791

207691_PM_x_at

207691_x_at

209473_PM_at

209473_at

209474_PM_s_at

209474_s_at

228585_PM_at

228585_at

3259257

3259261

3259262

3259279

3259280

3259283

3259284

3259285

3259286

3259287

3259288

3259289

3259290

3259291

3259292

3259293

3259294

3259295

3259296

3259297

3259298

3259299

3259300

3259301

3259304

3259306

3259307

3259308

3259309

3259310

3259311

3259312

3259313

3259314

3259315

3259316

3259317

3259318

32826_at

47051_at

7929511

953

A_14_P121845

A_14_P134563

A_23_P24260

A_24_P335025

A_33_P3218975

A_33_P3218980

A_33_P3262580

GE79307

GE88065

GO:0003824

GO:0003924

GO:0004050

GO:0004382

GO:0005515

GO:0005524

GO:0005886

GO:0005901

GO:0007155

GO:0007596

GO:0009134

GO:0016020

GO:0016787

GO:0016887

GO:0017110

GO:0017111

GO:0036384

GO:0043226

GO:0043262

GO:0043273

GO:0045134

GO:0055086

GO:0070062

GO:0070527

GO:0103023

GO:1990003

HMNXSV003014602

HMNXSV003016795

HMNXSV003033531

Hs.205353.1.S2_3p_at

Hs.7514.0.A1_3p_at

ILMN_1773125

PH_hs_0025943

PH_hs_0041105

S73813_at

g1842119_3p_a_at

Participates

as a component of

NTPDase1 [plasma membrane] (Homo sapiens)

Inferred To

ENTPD1 [plasma membrane] (Bos taurus)

ENTPD1 [plasma membrane] (Canis familiaris)

ENTPD1 [plasma membrane] (Gallus gallus)

ENTPD1 [plasma membrane] (Plasmodium falciparum)

ENTPD1 [plasma membrane] (Sus scrofa)

ENTPD1 [plasma membrane] (Xenopus tropicalis)

Entpd1 [plasma membrane] (Mus musculus)

Entpd1 [plasma membrane] (Rattus norvegicus)

Cross References

Guide to Pharmacology - Targets

2888

ENSEMBL

ENSP00000360250, ENSP00000390955, ENSG00000138185, ENST00000453258, ENST00000371205, ENST00000371207, ENSP00000360248, ENSP00000442968, ENST00000543964

OpenTargets

ENSG00000138185

GeneCards

ENTPD1

HPA

ENSG00000138185-ENTPD1

ZINC - Substances

ENTP1_HUMAN

ZINC target

P49961

PRO

P49961

Pharos - Targets

P49961

Orphanet

ENTPD1

ZINC - Predictions - Purchasable

ENTP1_HUMAN

HMDB Protein

HMDBP00084

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96S59 RANBP9	1	RANBP9 [cytosol] (R-HSA-374586)	0.581	5