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PRDM9 [nucleoplasm]
Stable Identifier
R-HSA-912345
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Histone-lysine N-methyltransferase PRDM9, PRDM9_HUMAN, KMT8B
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Meiosis (Homo sapiens)
Meiotic recombination (Homo sapiens)
PRDM9 binds recombination hotspot motifs in DNA (Homo sapiens)
PRDM9 [nucleoplasm] (Homo sapiens)
PRDM9:DNA [nucleoplasm] (Homo sapiens)
PRDM9 [nucleoplasm] (Homo sapiens)
PRDM9 trimethylates histone H3 (Homo sapiens)
PRDM9 [nucleoplasm] (Homo sapiens)
PRDM9:DNA [nucleoplasm] (Homo sapiens)
PRDM9 [nucleoplasm] (Homo sapiens)
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
PKMTs methylate histone lysines (Homo sapiens)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Homo sapiens)
Core MLL complex, SMYD3, PRDM9 [nucleoplasm] (Homo sapiens)
PRDM9 [nucleoplasm] (Homo sapiens)
Reproduction (Homo sapiens)
Meiosis (Homo sapiens)
Meiotic recombination (Homo sapiens)
PRDM9 binds recombination hotspot motifs in DNA (Homo sapiens)
PRDM9 [nucleoplasm] (Homo sapiens)
PRDM9:DNA [nucleoplasm] (Homo sapiens)
PRDM9 [nucleoplasm] (Homo sapiens)
PRDM9 trimethylates histone H3 (Homo sapiens)
PRDM9 [nucleoplasm] (Homo sapiens)
PRDM9:DNA [nucleoplasm] (Homo sapiens)
PRDM9 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NQV7 PRDM9
Gene Names
PRDM9, PFM6
Chain
chain:1-894
Reference Genes
BioGPS Gene:56979 PRDM9
COSMIC (genes):PRDM9 PRDM9
CTD Gene:56979 PRDM9
dbSNP Gene:56979 PRDM9
ENSEMBL:ENSG00000164256 PRDM9
HGNC:13994 PRDM9
KEGG Gene (Homo sapiens):56979 PRDM9
Monarch:56979 PRDM9
NCBI Gene:56979 PRDM9
OMIM:609760 PRDM9
UCSC:Q9NQV7 PRDM9
Reference Transcript
RefSeq:NM_001310214.1 PRDM9
RefSeq:NM_020227.3 PRDM9
Other Identifiers
11734227_at
11734228_x_at
11735930_s_at
16983550
221151_PM_at
221151_at
2804209
2804211
2804212
2804213
2804215
2804217
2804219
2804220
2804222
2804224
2804225
2804227
2804228
2804229
2804230
3705202
3705203
3705204
3705206
3705207
3705208
3705214
3705215
3705216
56979
8104634
A_23_P7612
A_24_P86246
GE509900
GO:0000003
GO:0000976
GO:0003674
GO:0003677
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0006259
GO:0006311
GO:0006325
GO:0006355
GO:0006464
GO:0006950
GO:0007049
GO:0007059
GO:0007129
GO:0007292
GO:0008150
GO:0008168
GO:0008219
GO:0009058
GO:0010468
GO:0010844
GO:0010845
GO:0016571
GO:0016584
GO:0016740
GO:0018024
GO:0022607
GO:0032259
GO:0034641
GO:0042054
GO:0042800
GO:0042803
GO:0043066
GO:0043167
GO:0043226
GO:0043565
GO:0044648
GO:0046872
GO:0046975
GO:0048232
GO:0051276
GO:0051321
GO:0051567
GO:0051568
GO:0080182
GO:0097198
GO:0097676
GO:0097692
GO:1905437
GO:1905516
GO:1990918
GO:2001255
PH_hs_0034307
TC05000114.hg
Participates
as a member of
Core MLL complex, SMYD3, PRDM9 [nucleoplasm] (Homo sapiens)
as an input of
PRDM9 binds recombination hotspot motifs in DNA (Homo sapiens)
as a component of
PRDM9:DNA [nucleoplasm] (Homo sapiens)
Inferred To
LOC100737218 [nucleoplasm]
(Sus scrofa)
PRDM9 [nucleoplasm]
(Danio rerio)
PRDM9 [nucleoplasm]
(Xenopus tropicalis)
LOC100851938 [nucleoplasm]
(Bos taurus)
Prdm9 [nucleoplasm]
(Mus musculus)
Prdm9 [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_001297143.1
,
NP_064612.2
OpenTargets
ENSG00000164256
IntEnz
2.1.1.361
,
2.1.1.354
,
2.1.1.362
,
2.1.1.359
HPA
ENSG00000164256-PRDM9
GeneCards
Q9NQV7
Ensembl
ENSG00000164256
,
ENST00000296682
,
ENSP00000296682
PRO
Q9NQV7
Pharos - Targets
Q9NQV7
HMDB Protein
HMDBP11898
PDB
4IJD
,
5EI9
,
5EGB
,
6NM4
,
5EH2
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