Reactome | PRDM9 [nucleoplasm]

PRDM9 [nucleoplasm]

Stable Identifier

R-HSA-912345

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Histone-lysine N-methyltransferase PRDM9, PRDM9_HUMAN, KMT8B

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9NQV7 PRDM9

Gene Names

PRDM9, PFM6

Chain

chain:1-894

Reference Genes

BioGPS Gene:56979 PRDM9

COSMIC (genes):PRDM9 PRDM9

CTD Gene:56979 PRDM9

dbSNP Gene:56979 PRDM9

ENSEMBL:ENSG00000164256 PRDM9

HGNC:13994 PRDM9

KEGG Gene (Homo sapiens):56979 PRDM9

Monarch:56979 PRDM9

NCBI Gene:56979 PRDM9

OMIM:609760 PRDM9

UCSC:Q9NQV7 PRDM9

Reference Transcript

Other Identifiers

11734227_at

11734228_x_at

11735930_s_at

16983550

221151_at

2804209

2804211

2804212

2804213

2804215

2804217

2804219

2804220

2804222

2804224

2804225

2804227

2804228

2804229

2804230

3705202

3705203

3705204

3705206

3705207

3705208

3705214

3705215

3705216

56979

8104634

A_23_P7612

A_24_P86246

GE509900

GO:0000003

GO:0000976

GO:0003674

GO:0003676

GO:0003677

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0006259

GO:0006311

GO:0006325

GO:0006355

GO:0006464

GO:0006950

GO:0007049

GO:0007059

GO:0007129

GO:0007292

GO:0008150

GO:0008168

GO:0008219

GO:0009058

GO:0010468

GO:0010844

GO:0010845

GO:0016584

GO:0016740

GO:0018024

GO:0022607

GO:0032259

GO:0034641

GO:0042800

GO:0042803

GO:0043066

GO:0043167

GO:0043226

GO:0043565

GO:0044648

GO:0046872

GO:0046975

GO:0048232

GO:0051276

GO:0051321

GO:0051567

GO:0051568

GO:0080182

GO:0097198

GO:0097676

GO:0097692

GO:1905437

GO:1905516

GO:1990918

GO:2001255

PH_hs_0034307

TC05000114.hg

Participates

as a member of

Core MLL complex, SMYD3, PRDM9 [nucleoplasm] (Homo sapiens)

as an input of

PRDM9 binds recombination hotspot motifs in DNA (Homo sapiens)

as a component of

PRDM9:DNA [nucleoplasm] (Homo sapiens)

Inferred To

Homologues of PRDM9 [nucleoplasm] (Danio rerio)

Homologues of PRDM9 [nucleoplasm] (Xenopus tropicalis)

znf91 [nucleoplasm] (Xenopus tropicalis)

gfi1b [nucleoplasm] (Danio rerio)

PRDM9 [nucleoplasm] (Danio rerio)

PRDM9 [nucleoplasm] (Xenopus tropicalis)

Prdm9 [nucleoplasm] (Mus musculus)

Prdm9 [nucleoplasm] (Rattus norvegicus)

PRDM7 [nucleoplasm] (Bos taurus)

Cross References

RefSeq

NP_064612.2, NP_001297143.1

OpenTargets

ENSG00000164256

IntEnz

2.1.1.362, 2.1.1.361, 2.1.1.359

GeneCards

Q9NQV7

HPA

ENSG00000164256-PRDM9

Ensembl

ENST00000296682, ENSP00000296682, ENSG00000164256

PRO

Q9NQV7

HMDB Protein

HMDBP11898

PDB

4IJD, 5EH2, 5EGB, 6NM4, 5EI9