Maresin-like SPMs translocate from cytosol to extracellular region

Stable Identifier
R-HSA-9031803
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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To produce their pro-resolving effects, maresin-like SPMs (MaR-L1, MaR-L2, 14(S), 21(R/S)-diHDHA and 14(R), 21(R/S)-diHDHA) are released into the exudate of local inflammation sites (Hong et al. 2014). The mechanism of translocation is unknown.
Literature References
PubMed ID Title Journal Year
25200603 Maresin-like lipid mediators are produced by leukocytes and platelets and rescue reparative function of diabetes-impaired macrophages

Alapure, BV, Lu, Y, Tian, H, Bunnell, BA, Wang, Q, Hong, S, Laborde, JM

Chem. Biol. 2014
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