Insulin secretory granule translocates across the cortical actin network

Stable Identifier
R-HSA-9023171
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
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Insulin-containing secretory granules are bound to Myosin Va via Rab27a in a complex of uncertain composition. Myosin Va motors along the cortical actin network (actin at the periphery of the cytoplasm), carrying the granules to the inner surface of the plasma membrane (inferred from mouse MIN6 cells).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
microfilament motor activity of MYO5A:MYRIP:RAB27A [cytosol]
Physical Entity
Activity
Inferred From
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Created