MOBP gene expression is inhibited by MECP2

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R-HSA-9022870
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Reaction [omitted]
Species
Homo sapiens
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Based on studies in mice, MECP2 directly inhibits transcription of the MOBP gene, encoding myelin-associated oligodendrocyte basic protein. Mopb levels are increased in Mecp2 null mice (Urdinguio et al. 2008). MECP2-mediated inhibition of MOBP transcription was also reported in rats (Sharma et al. 2015).

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