Reactome | RHOT1 binds effectors at the mitochondrial outer membrane

RHOT1 binds effectors at the mitochondrial outer membrane

Stable Identifier

R-HSA-9018815

Type

Reaction [binding]

Species

Homo sapiens

Compartment

mitochondrial outer membrane, cytosol

ReviewStatus

5/5

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RHOT1 binds effectors at the mitochondrial outer membrane

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Active GTP-bound RHOT1 interacts with the following effectors:
MYO19 (Oeding et al. 2018)
TRAK1 (Fransson et al. 2006)
TRAK2 (Fransson et al. 2006; MacAskill et al. 2009)

Literature References

PubMed ID	Title	Journal	Year
16630562	The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking Fransson, S, Ruusala, A, Aspenström, P	Biochem. Biophys. Res. Commun.	2006
19103291	GTPase dependent recruitment of Grif-1 by Miro1 regulates mitochondrial trafficking in hippocampal neurons MacAskill, AF, Brickley, K, Stephenson, FA, Kittler, JT	Mol. Cell. Neurosci.	2009
30111583	Identification of Miro1 and Miro2 as mitochondrial receptors for myosin XIX Oeding, SJ, Majstrowicz, K, Hu, XP, Schwarz, V, Freitag, A, Honnert, U, Nikolaus, P, Bähler, M	J. Cell. Sci.	2018