RHOT1 binds effectors at the mitochondrial outer membrane

Stable Identifier
R-HSA-9018815
Type
Reaction [binding]
Species
Homo sapiens
Compartment
mitochondrial outer membrane, cytosol
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RHOT1 binds effectors at the mitochondrial outer membrane
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Active GTP-bound RHOT1 interacts with the following effectors:
MYO19 (Oeding et al. 2018)
TRAK1 (Fransson et al. 2006)
TRAK2 (Fransson et al. 2006; MacAskill et al. 2009)

Literature References
PubMed ID Title Journal Year
19103291 GTPase dependent recruitment of Grif-1 by Miro1 regulates mitochondrial trafficking in hippocampal neurons

MacAskill, AF, Brickley, K, Stephenson, FA, Kittler, JT

Mol. Cell. Neurosci. 2009
16630562 The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking

Fransson, S, Ruusala, A, Aspenström, P

Biochem. Biophys. Res. Commun. 2006
30111583 Identification of Miro1 and Miro2 as mitochondrial receptors for myosin XIX

Oeding, SJ, Majstrowicz, K, Hu, XP, Schwarz, V, Freitag, A, Honnert, U, Nikolaus, P, Bähler, M

J. Cell. Sci. 2018
Participants
Input
Output
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as an event of
Orthologous Events
RHOT1 binds effectors at the mitochondrial outer membrane (Caenorhabditis elegans)
RHOT1 binds effectors at the mitochondrial outer membrane (Canis familiaris)
RHOT1 binds effectors at the mitochondrial outer membrane (Danio rerio)
RHOT1 binds effectors at the mitochondrial outer membrane (Dictyostelium discoideum)
RHOT1 binds effectors at the mitochondrial outer membrane (Drosophila melanogaster)
RHOT1 binds effectors at the mitochondrial outer membrane (Gallus gallus)
RHOT1 binds effectors at the mitochondrial outer membrane (Mus musculus)
RHOT1 binds effectors at the mitochondrial outer membrane (Rattus norvegicus)
RHOT1 binds effectors at the mitochondrial outer membrane (Saccharomyces cerevisiae)
RHOT1 binds effectors at the mitochondrial outer membrane (Schizosaccharomyces pombe)
RHOT1 binds effectors at the mitochondrial outer membrane (Sus scrofa)
Authored
Orlic-Milacic, M  (2020-07-14)
Reviewed
Schrader, M  (2021-02-09)
Castro, IG  (2021-02-09)
Created
Orlic-Milacic, M  (2017-09-05)
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