Reactome | MAN1B1 [endoplasmic reticulum quality control compartment]

MAN1B1 [endoplasmic reticulum quality control compartment]

Stable Identifier

R-HSA-901013

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum quality control compartment

Synonyms

Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, MA1B1_HUMAN

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Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - SARS-CoV-2 Infection (Homo sapiens)
        
        Late SARS-CoV-2 Infection Events (Homo sapiens)
        
        Translation of Structural Proteins (Homo sapiens)
        
        Maturation of spike protein (Homo sapiens)
        
        N-glycan mannose trimming of Spike (Homo sapiens)
        
        MAN1B1,EDEM2 [endoplasmic reticulum quality control compartment] (Homo sapiens)
        
        MAN1B1 [endoplasmic reticulum quality control compartment] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9UKM7 MAN1B1

Gene Names

MAN1B1, UNQ747/PRO1477

Chain

chain:1-699

Reference Genes

BioGPS Gene:11253 MAN1B1

COSMIC (genes):MAN1B1 MAN1B1

CTD Gene:11253 MAN1B1

dbSNP Gene:11253 MAN1B1

ENSEMBL:ENSG00000177239 MAN1B1

ENSEMBL_homo_sapiens_GENE:ENSG00000177239.16 MAN1B1

HGNC:6823 MAN1B1

KEGG Gene (Homo sapiens):11253 MAN1B1

Monarch:11253 MAN1B1

NCBI Gene:11253 MAN1B1

OMIM:604346 MAN1B1

UCSC:Q9UKM7 MAN1B1

Reference Transcript

RefSeq:NM_016219.4 MAN1B1

Other Identifiers

11253

11721458_s_at

11752272_a_at

11754647_x_at

17091571

218636_PM_s_at

218636_s_at

3195176

3195177

3195178

3195180

3195184

3195188

3195189

3195191

3195194

3195195

3195198

3195199

3195212

3195215

3195217

3195218

3195219

3195221

3195222

3195223

3195224

3195225

3195226

3195227

3195228

3195229

3195230

64339_s_at

65884_PM_at

65884_at

8159566

A_14_P133434

A_23_P94857

GE58443

GO:0003824

GO:0004559

GO:0004571

GO:0005509

GO:0005576

GO:0005783

GO:0005789

GO:0005794

GO:0005975

GO:0006058

GO:0006486

GO:0008152

GO:0009100

GO:0009311

GO:0016020

GO:0016787

GO:0016798

GO:0019082

GO:0030163

GO:0030433

GO:0031410

GO:0036211

GO:0036503

GO:0036508

GO:0043226

GO:0044322

GO:0046872

GO:1901135

GO:1903561

HMNXSV003001922

ILMN_1771957

PH_hs_0014418

TC09000838.hg

g7706436_3p_s_at

Participates

as a member of

MAN1B1,EDEM2 [endoplasmic reticulum quality control compartment] (Homo sapiens)

Other forms of this molecule

MAN1B1 R334C [endoplasmic reticulum quality control compartment]

MAN1B1 W473* [endoplasmic reticulum quality control compartment]

MAN1B1 E397K [endoplasmic reticulum quality control compartment]

Cross References

RefSeq

NP_057303.2

OpenTargets

ENSG00000177239

HPA

ENSG00000177239-MAN1B1

GeneCards

Q9UKM7

ZINC target

Q9UKM7

Ensembl

ENSG00000177239, ENST00000371589, ENSP00000360645

PRO

Q9UKM7

Pharos - Targets

Q9UKM7

Orphanet

20401

HMDB Protein

HMDBP00869

PDB

5KK7, 1FO2, 5KIJ, 1FMI, 1X9D, 1FO3