IL34 binds CSF1

Stable Identifier
R-HSA-9009488
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
IL34 binds CSF1
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Interleukin-34 (IL34) can bind Macrophage colony-stimulating factor 1 (CSF1) to form a heteromer, which subsequently binds CSF1R (Segaliny et al. 2015).

Literature References
PubMed ID Title Journal Year
26095744 IL-34 and M-CSF form a novel heteromeric cytokine and regulate the M-CSF receptor activation and localization

Ségaliny, AI, Brulin, B, Téletchéa, S, Maillasson, M, Charrier, C, Heymann, D, Brion, R

Cytokine 2015
Participants
Input
Output
Participates
as an event of
Orthologous Events
IL34 binds CSF1 (Bos taurus)
IL34 binds CSF1 (Canis familiaris)
IL34 binds CSF1 (Danio rerio)
IL34 binds CSF1 (Gallus gallus)
IL34 binds CSF1 (Mus musculus)
IL34 binds CSF1 (Rattus norvegicus)
IL34 binds CSF1 (Sus scrofa)
Authored
Varusai, TM  (2017-06-19)
Reviewed
Meldal, BH  (2017-11-03)
Created
Varusai, TM  (2017-06-19)
Cite Us!