RUNX2 binds SOX9

Stable Identifier
R-HSA-8985343
Type
Reaction
Species
Homo sapiens
Compartment
nucleoplasm
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RUNX2 binds SOX9
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SOX9 binds to RUNX2 and represses its transcriptional activity (Zhou et al. 2006).

Literature References
PubMed ID Title Journal Year
17142326 Dominance of SOX9 function over RUNX2 during skeletogenesis

Munivez, E, Sebald, E, Zheng, Q, Zhou, G, Chen, Y, Lee, B, Krakow, D, Engin, F

Proc. Natl. Acad. Sci. U.S.A. 2006
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Orthologous Events
RUNX2 binds SOX9 (Bos taurus)
RUNX2 binds SOX9 (Danio rerio)
RUNX2 binds SOX9 (Drosophila melanogaster)
RUNX2 binds SOX9 (Gallus gallus)
RUNX2 binds SOX9 (Mus musculus)
RUNX2 binds SOX9 (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2017-04-13)
Reviewed
Ducy, P  (2017-08-04)
Created
Orlic-Milacic, M  (2017-04-13)
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