Expression of STAT5 upregulated genes

Stable Identifier
R-HSA-8983011
Type
Reaction [omitted]
Species
Homo sapiens
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Interleukin-7 (IL7) stimulation upregulates expression of the transcripts and proteins encoding Cytokine-inducible SH2-containing protein (CISH), Suppressor of cytokine signaling 1 (SOCS1) and Suppressor of cytokine signaling 2 (SOCS2) in CD8+ T cells (Ghazawi et al. 2016).
This is a black-box event since details of the mechanism of transcription and translation are omitted.

Literature References
PubMed ID Title Journal Year
27423467 Suppressor of cytokine signaling (SOCS) proteins are induced by IL-7 and target surface CD127 protein for degradation in human CD8 T cells

Ghazawi, FM, Faller, EM, Parmar, P, El-Salfiti, A, MacPherson, PA

Cell. Immunol. 2016
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