LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA

Stable Identifier
R-HSA-8980228
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Dimeric lipase G (LIPG) catalyzes the hydrolysis of triglycerides (TAG) associated with high-density lipoprotein particles to diglycerides (DAG) and long-chain fatty acids (LCFA) (Griffon et al. 2009).
Literature References
PubMed ID Title Journal Year
19567873 Identification of the active form of endothelial lipase, a homodimer in a head-to-tail conformation

Saven, JG, Jin, W, Glick, JM, Kempner, ES, Badellino, KO, Rader, DJ, Marchadier, DH, Griffon, N, Millar, J, Petty, TJ, Billheimer, J

J. Biol. Chem. 2009
Participants
Participates
Catalyst Activity

lipoprotein lipase activity of LIPG dimer [extracellular region]

Orthologous Events
Authored
Reviewed
Created
Cite Us!