LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA

Stable Identifier
R-HSA-8980228
Type
Reaction [transition]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
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LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA
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Dimeric lipase G (LIPG) catalyzes the hydrolysis of triglycerides (TAG) associated with high-density lipoprotein particles to diglycerides (DAG) and long-chain fatty acids (LCFA) (Griffon et al. 2009).
Literature References
PubMed ID Title Journal Year
19567873 Identification of the active form of endothelial lipase, a homodimer in a head-to-tail conformation

Griffon, N, Jin, W, Petty, TJ, Millar, J, Badellino, KO, Saven, JG, Marchadier, DH, Kempner, ES, Billheimer, J, Glick, JM, Rader, DJ

J. Biol. Chem. 2009
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Output
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as an event of
Catalyst Activity

lipoprotein lipase activity of LIPG dimer [extracellular region]

Physical Entity
LIPG dimer [extracellular region] (Homo sapiens)
Activity
lipoprotein lipase activity (GO:0004465)
Orthologous Events
LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA (Bos taurus)
LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA (Canis familiaris)
LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA (Danio rerio)
LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA (Drosophila melanogaster)
LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA (Gallus gallus)
LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA (Mus musculus)
LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA (Rattus norvegicus)
LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA (Sus scrofa)
LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA (Xenopus tropicalis)
Authored
Jassal, B  (2015-07-30)
Reviewed
D'Eustachio, P  (2015-09-14)
Created
D'Eustachio, P  (2017-02-27)
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