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LPIN1 gene [nucleoplasm]
Stable Identifier
R-HSA-8962866
Type
DNA Sequence [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Epigenetic regulation by WDR5-containing histone modifying complexes (Homo sapiens)
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Homo sapiens)
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes (Homo sapiens)
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis (Homo sapiens)
Coactivators are recruited to liganded PPARG:RXRA heterodimer (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:LPIN1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
PPARG ligands:PPARG:RXRA ligands:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:Ligand-bound RXRA:LPIN1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
Corepressors are released from liganded PPARG:RXRA heterodimer (Homo sapiens)
PPARG ligands:PPARG:RXRA ligands:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:LPIN1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
PPARG ligands:PPARG:RXRA ligands:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:Ligand-bound RXRA:LPIN1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
KMT2D,(KMT2C) complex monomethylates nucleosomes at PPARG:RXRA-bound enhancers (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:H3K4me1-Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:LPIN1 gene:H3K4me1-Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
LPIN1 gene:H3K4me1-nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:MLL4,(MLL3)-ASCOM:LPIN1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
LPIN1 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)
Activated PPARG:RXRA:LPIN1 gene:H3K4me1-Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
LPIN1 gene:H3K4me1-nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
MLL4-ASCOM,(MLL3-ASCOM) complex is recruited to ligand- and coactivator-bound PPARG:RXRA heterodimer (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:LPIN1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:MLL4,(MLL3)-ASCOM:LPIN1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
PPARG binds ligands (Homo sapiens)
PPARG ligands:PPARG:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:RXRA:NCoR/SMRT:LPIN1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
PPARG:RXRA:NCoR/SMRT:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
PPARG:RXRA:NCoR/SMRT:LPIN1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
PPARG:RXRA heterodimer binds target gene loci (Homo sapiens)
Adipogenesis target genes of PPARG and MLL3/4:Nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
PPARG:RXRA:Adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
PPARG:RXRA:LPIN1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
RXRA binds ligands (Homo sapiens)
PPARG ligands:PPARG:RXRA ligands:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:LPIN1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
PPARG ligands:PPARG:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:RXRA:NCoR/SMRT:LPIN1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci (Homo sapiens)
PPARG:RXRA:Adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
PPARG:RXRA:LPIN1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
PPARG:RXRA:NCoR/SMRT:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
PPARG:RXRA:NCoR/SMRT:LPIN1 gene:nucleosomes [nucleoplasm] (Homo sapiens)
LPIN1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
LPIN1 gene [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
ENSEMBL:ENSG00000134324 LPIN1
Gene Names
LPIN1, KIAA0188
Participates
as a component of
LPIN1 gene:Nucleosome [nucleoplasm] (Homo sapiens)
LPIN1 gene:H3K4me1-nucleosomes [nucleoplasm] (Homo sapiens)
as an input of
LPIN1 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)
Inferred To
Ghost homologue of LPIN1 gene [nucleoplasm]
(Bos taurus)
Ghost homologue of LPIN1 gene [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of LPIN1 gene [nucleoplasm]
(Canis familiaris)
Ghost homologue of LPIN1 gene [nucleoplasm]
(Danio rerio)
Ghost homologue of LPIN1 gene [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of LPIN1 gene [nucleoplasm]
(Gallus gallus)
Ghost homologue of LPIN1 gene [nucleoplasm]
(Mus musculus)
Ghost homologue of LPIN1 gene [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of LPIN1 gene [nucleoplasm]
(Sus scrofa)
Ghost homologue of LPIN1 gene [nucleoplasm]
(Xenopus tropicalis)
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