CCNA1 gene expression is stimulated by E2F1

Stable Identifier
R-HSA-8961895
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
nucleoplasm
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CCNA1 gene expression is stimulated by E2F1
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E2F1 directly stimulates transcription of the CCNA1 gene, encoding cyclin A1 (DeGregori et al. 1995, Liu et al. 1998).

Literature References
PubMed ID Title Journal Year
7623816 Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

Nevins, JR, DeGregori, J, Kowalik, T

Mol Cell Biol 1995
9662327 A new model of cell cycle-regulated transcription: repression of the cyclin A promoter by CDF-1 and anti-repression by E2F

Müller, R, Engeland, K, Lucibello, FC, Liu, N

Oncogene 1998
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
E2F1:TFDP1,TFDP2:CCNA1 gene [nucleoplasm] (Homo sapiens)
Active Unit
E2F1:TFDP1,TFDP2 [nucleoplasm]
Authored
Gopinathrao, G  (2004-06-16)
Reviewed
Bosco, G  (2004-06-16)
Created
Orlic-Milacic, M  (2017-02-06)
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