CCNA1 gene expression is stimulated by E2F1

Stable Identifier
R-HSA-8961895
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
CCNA1 gene expression is stimulated by E2F1
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

E2F1 directly stimulates transcription of the CCNA1 gene, encoding cyclin A1 (DeGregori et al. 1995, Liu et al. 1998).

Literature References
PubMed ID Title Journal Year
9662327 A new model of cell cycle-regulated transcription: repression of the cyclin A promoter by CDF-1 and anti-repression by E2F

Liu, N, Lucibello, FC, Engeland, K, Müller, R

Oncogene 1998
7623816 Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

DeGregori, J, Kowalik, T, Nevins, JR

Mol Cell Biol 1995
Participants
Input
Output
Participant Of
hasEvent
This event is regulated
Positively by
Authored
Gopinathrao, G  (2004-06-16)
Reviewed
Bosco, G  (2004-06-16)
Created
Orlic-Milacic, M  (2017-02-06)