E2F1 binds the ORC1 gene promoter

Stable Identifier
R-HSA-8961671
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

E2F1 binds to E2F binding sites in the promoter of the ORC1 gene (Ohtani et al. 1996, Ohtani et al. 1998). It has been observed in Drosophila that E2F1 regulated expression of Orc1 stimulates ORC1-6 complex formation and binding to the origin of replication (Asano and Wharton, 1999).

Participants
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