Reactome | UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1

UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1

Stable Identifier

R-HSA-8948018

Type

Reaction [BlackBoxEvent]

Species

Homo sapiens

Compartment

cytosol

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UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1

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Following the TRAF6-mediated transfer of ubiquitin from the E2 conjugating enzyme UBE2N:UBE2V1 it dissociates.

Literature References

PubMed ID	Title	Journal	Year
17135271	Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation Lamothe, B, Wu, H, Darnay, BG, Besse, A, Campos, AD, Webster, WK	J Biol Chem	2007