miR-21-5p, one of the two mature products of miR-21, binds the 3'UTR of PTEN mRNA to inhibit PTEN mRNA translation. miR-21 only affects PTEN protein level and thus presumably functions as part of the nonendonucleolytic RISC (Meng et al. 2007, Zhang et al. 2010)
Yang, GH, Liu, Q, Wang, JJ, Zhang, JG, Jiang, K, Zhao, F
Wehbe-Janek, H, Patel, T, Meng, F, Henson, R, Jacob, ST, Ghoshal, K
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