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cleaved GPI-ALPPL2 [extracellular region]
Stable Identifier
R-HSA-8943384
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Alkaline phosphatase, placental-like ecNumber3.1.3.1/ecNumber, PPBN_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Post-translational modification: synthesis of GPI-anchored proteins (Homo sapiens)
GPLD1 hydrolyses GPI-anchors from proteins (Homo sapiens)
proteins with cleaved GPI-anchors [extracellular region] (Homo sapiens)
cleaved GPI-ALPPL2 dimer [extracellular region] (Homo sapiens)
cleaved GPI-ALPPL2 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P10696 ALPG
Gene Names
ALPG, ALPPL, ALPPL2
Chain
signal peptide:1-19, chain:20-503, propeptide:504-532
Reference Genes
BioGPS Gene:251 ALPG
COSMIC (genes):ALPG ALPG
CTD Gene:251 ALPG
dbSNP Gene:251 ALPG
ENSEMBL:ENSG00000163286 ALPPL2
HGNC:441 ALPG
Monarch:251 ALPG
NCBI Gene:251 ALPG
OMIM:171810 ALPG
UCSC:P10696 ALPG
Reference Transcript
RefSeq:NM_031313.2 ALPG
Other Identifiers
11727334_at
16892246
210431_PM_at
210431_at
211619_PM_s_at
211619_s_at
216377_3p_x_at
216377_PM_x_at
216377_x_at
251
2532277
2532278
2532279
2532280
2532282
2532284
2532285
2532286
2532287
2532288
2532290
2532297
2532298
2532299
2532300
2532301
2532302
2532303
2532304
2532305
2532306
2532307
2532308
2532309
2532310
2532311
678_at
8049128
80616_at
8180197
A_23_P68183
A_24_P131580
GO:0003824
GO:0004035
GO:0005576
GO:0005886
GO:0016787
GO:0016791
GO:0046872
GO:0098552
HMNXSV003037912
HMNXSV003046281
Hs.284255.2.S1_3p_s_at
J04948_at
PH_hs_0029764
TC02001399.hg
g178418_3p_at
g178471_3p_s_at
Participates
as a component of
cleaved GPI-ALPPL2 dimer [extracellular region] (Homo sapiens)
Other forms of this molecule
GPI-ALPPL2 [plasma membrane]
Inferred To
Homologues of cleaved GPI-ALPI [extracellular region]
(Danio rerio)
Homologues of cleaved GPI-ALPI [extracellular region]
(Drosophila melanogaster)
Homologues of cleaved GPI-ALPPL2 [extracellular region]
(Bos taurus)
Homologues of cleaved GPI-ALPPL2 [extracellular region]
(Mus musculus)
Homologues of cleaved GPI-ALPPL2 [extracellular region]
(Rattus norvegicus)
Homologues of cleaved GPI-ALPPL2 [extracellular region]
(Sus scrofa)
cleaved GPI-ALPPL2 [extracellular region]
(Bos taurus)
cleaved GPI-ALPPL2 [extracellular region]
(Mus musculus)
cleaved GPI-ALPPL2 [extracellular region]
(Rattus norvegicus)
cleaved GPI-ALPPL2 [extracellular region]
(Sus scrofa)
cleaved GPI-ALPI [extracellular region]
(Bos taurus)
cleaved GPI-ALPI [extracellular region]
(Canis familiaris)
cleaved GPI-ALPI [extracellular region]
(Danio rerio)
cleaved GPI-ALPI [extracellular region]
(Drosophila melanogaster)
cleaved GPI-ALPI [extracellular region]
(Gallus gallus)
cleaved GPI-ALPI [extracellular region]
(Mus musculus)
cleaved GPI-ALPI [extracellular region]
(Rattus norvegicus)
cleaved GPI-ALPI [extracellular region]
(Sus scrofa)
cleaved GPI-ALPI [extracellular region]
(Xenopus tropicalis)
Modified Residues
Name
L-aspartic acid 1-amide (6-O-(2-aminoethylphosphono)-alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-D-myo-inositol group) at 503
Coordinate
503
Modification
6-O-(2-aminoethylphosphono)-alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-D-myo-inositol group
PsiMod Name
L-aspartic acid 1-amide
PsiMod Definition
A protein modification that effectively converts an L-aspartic acid residue to L-aspartic acid 1-amide.
Cross References
ENSEMBL
ENSP00000295453
,
ENST00000295453
OpenTargets
ENSG00000163286
IntEnz
3.1.3.1
HPA
ENSG00000163286-ALPG
ZINC - Substances
PPBN_HUMAN
ZINC target
P10696
PRO
P10696
Pharos - Targets
P10696
GlyGen
P10696
HMDB Protein
HMDBP00099
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q6Y288 B3GLCT
2
B3GALTL G393E [endoplasmic reticulum membrane]
(R-HSA-9632239)
B3GALTL [endoplasmic reticulum membrane]
(R-HSA-5173226)
0.527
3
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