miR-27a binds RUNX1 mRNA

Stable Identifier
R-HSA-8937134
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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miR-27a binds RUNX1 mRNA
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MicroRNA miR-27a binds the 3'UTR of the RUNX1 mRNA. As miR-27a inhibits translation of the RUNX1 mRNA without affecting the RUNX1 mRNA stability, miR-27a is assumed to function within the nonendonucleolytic RISC (Ben-Ami et al. 2009).
Literature References
PubMed ID Title Journal Year
19114653 A regulatory interplay between miR-27a and Runx1 during megakaryopoiesis

Groner, Y, Pencovich, N, Lotem, J, Levanon, D, Ben-Ami, O

Proc. Natl. Acad. Sci. U.S.A. 2009
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Authored
Orlic-Milacic, M  (2016-09-14)
Reviewed
Chuang, LS  (2016-12-20)
Ito, Y  (2016-12-20)
Created
Orlic-Milacic, M  (2016-08-29)
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