RUNX1 and ESR1 bind the KCTD6 gene enhancer

Stable Identifier
R-HSA-8932037
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
RUNX1 and ESR1 cooperatively bind the KCTD6 gene enhancer, which contains both estrogen response elements and RUNX1 response elements (Stender et al. 2010).
Literature References
PubMed ID Title Journal Year
20547749 Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation

Kraus, WL, Stender, JD, Benner, C, Charn, TH, Kim, K, Chang, KC, Katzenellenbogen, BS, Glass, CK, Komm, B

Mol. Cell. Biol. 2010
Participants
Participates
Authored
Reviewed
Created
Cite Us!