MET binds TNS3

Stable Identifier
R-HSA-8875523
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Activated MET receptor binds to tensin-3 (TNS3). The functional role of this interaction is not known. TNS3 is downregulated in colorectal, lung, ovarian and gastric cancers that show upregulation of tensin-4 (TNS4) (Muharram et al. 2014).

Literature References
PubMed ID Title Journal Year
24814316 Tensin-4-dependent MET stabilization is essential for survival and proliferation in carcinoma cells

Muharram, G, Sahgal, P, Korpela, T, De Franceschi, N, Kaukonen, R, Clark, K, Tulasne, D, Carpén, O, Ivaska, J

Dev. Cell 2014
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created