LRIG1 undergoes ubiquitination

Stable Identifier
R-HSA-8875431
Type
Reaction
Species
Homo sapiens
Compartment
cytosol, plasma membrane
Locations in the PathwayBrowser
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Summation

Upon binding to MET, LRIG1 undergoes ubiquitination by an unknown ubiquitin ligase (Oh et al. 2014).

Literature References
PubMed ID Title Journal Year
24828152 USP8 modulates ubiquitination of LRIG1 for Met degradation

Oh, YM, Lee, SB, Choi, J, Suh, HY, Shim, S, Song, YJ, Kim, B, Lee, JM, Oh, SJ, Jeong, Y, Cheong, KH, Song, PH, Kim, KA

Sci Rep 2014
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
ubiquitin protein ligase activity of unknown ubiquitin ligase [cytosol]
Physical Entity
unknown ubiquitin ligase [cytosol]
Activity
ubiquitin protein ligase activity (0061630)
Authored
Orlic-Milacic, M  (2016-06-14)
Reviewed
Heynen, G  (2016-07-11)
Birchmeier, W  (2016-07-11)