ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH

Stable Identifier
R-HSA-8874745
Type
Reaction
Species
Homo sapiens
Compartment
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Mitochondrial 3-ketoacyl-CoA thiolase (ACAA2) is a mitochondrial matrix enzyme involved in fatty acid beta-oxidation, transferring the acyl group from acyl-CoA (acyl-CoA) to acetyl-CoA (Ac-CoA) to form 3-oxyoacyl-CoA (3OA-CoA) and CoA-SH (Abe et al. 1993, Middleton 1973).

Literature References
PubMed ID Title Journal Year
8241273 Cloning and sequence analysis of a full length cDNA encoding human mitochondrial 3-oxoacyl-CoA thiolase

Abe, H, Suzuki, Y, Takayanagi, M, Sakuraba, H, Ohtake, A, Takiguchi, M, Yamamoto, S, Amaya, Y, Mori, M, Satoh, Y

Biochim. Biophys. Acta 1993
4721607 The oxoacyl-coenzyme A thiolases of animal tissues

Middleton, B

Biochem. J. 1973
Participants
Participates
Catalyst Activity

acetyl-CoA C-acyltransferase activity of ACAA2 tetramer [mitochondrial matrix]

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