Mitochondrial 3-ketoacyl-CoA thiolase (ACAA2) is a mitochondrial matrix enzyme involved in fatty acid beta-oxidation, transferring the acyl group from acyl-CoA (acyl-CoA) to acetyl-CoA (Ac-CoA) to form 3-oxyoacyl-CoA (3OA-CoA) and CoA-SH (Abe et al. 1993, Middleton 1973).
Abe, H, Suzuki, Y, Takayanagi, M, Sakuraba, H, Ohtake, A, Takiguchi, M, Yamamoto, S, Amaya, Y, Mori, M, Satoh, Y
Middleton, B
acetyl-CoA C-acyltransferase activity of ACAA2 tetramer [mitochondrial matrix]
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