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GGC-RAB8B [cytosol]
Stable Identifier
R-HSA-8874068
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ras-related protein Rab-8B, RAB8B_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
RAB geranylgeranylation (Homo sapiens)
RGGT geranylgeranylates RAB proteins (Homo sapiens)
CHMs:GGC-RABs:GDP [cytosol] (Homo sapiens)
GGC-RABs:GDP [cytosol] (Homo sapiens)
GGC-RABs [cytosol] (Homo sapiens)
GGC-RAB8B [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
RAB8 GEFs exchange GTP for GDP on RAB8 (Homo sapiens)
GGC-RAB8:GDP:GDIs,CHMs [cytosol] (Homo sapiens)
GGC-RAB8:GDP [cytosol] (Homo sapiens)
GGC-RAB8 [cytosol] (Homo sapiens)
GGC-RAB8B [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q92930 RAB8B
Gene Names
RAB8B
Chain
chain:1-204, propeptide:205-207
Reference Genes
BioGPS Gene:51762 RAB8B
COSMIC (genes):RAB8B RAB8B
CTD Gene:51762 RAB8B
dbSNP Gene:51762 RAB8B
ENSEMBL:ENSG00000166128 RAB8B
ENSEMBL_homo_sapiens_GENE:ENSG00000166128.13 RAB8B
HGNC:30273 RAB8B
KEGG Gene (Homo sapiens):51762 RAB8B
Monarch:51762 RAB8B
NCBI Gene:51762 RAB8B
OMIM:613532 RAB8B
UCSC:Q92930 RAB8B
Reference Transcript
RefSeq:NM_016530.2 RAB8B
Other Identifiers
11720798_at
11720799_s_at
11720800_a_at
11751370_a_at
16801850
219210_PM_s_at
219210_s_at
222846_PM_at
222846_at
226633_PM_at
226633_at
3597479
3597497
3597498
3597499
3597500
3597503
3597505
3597508
3597511
3597512
3597513
3597514
3597515
3597516
3597517
51762
55673_at
59515_at
7984112
88528_at
A_23_P317465
A_23_P37535
GE55695
GE79670
GO:0000166
GO:0002376
GO:0003824
GO:0003924
GO:0005102
GO:0005515
GO:0005525
GO:0005576
GO:0005615
GO:0005768
GO:0005777
GO:0005778
GO:0005886
GO:0006886
GO:0006904
GO:0007031
GO:0008021
GO:0009306
GO:0010008
GO:0015031
GO:0016020
GO:0016192
GO:0016787
GO:0017157
GO:0019003
GO:0019882
GO:0023052
GO:0030140
GO:0030670
GO:0030911
GO:0031346
GO:0031410
GO:0032456
GO:0034330
GO:0043226
GO:0045046
GO:0045335
GO:0048210
GO:0048471
GO:0050886
GO:0051286
GO:0051461
GO:0055038
GO:0061024
GO:0070062
GO:0072659
GO:0098793
GO:0150115
HMNXSV003020669
Hs.321245.0.S2_3p_at
Hs.95388.0.A1_3p_at
ILMN_2173004
PH_hs_0024044
TC15000581.hg
g7706562_3p_s_at
Participates
as a candidate of
GGC-RAB8 [cytosol] (Homo sapiens)
GGC-RABs [cytosol] (Homo sapiens)
Other forms of this molecule
RAB8B [recycling endosome membrane]
GGC-RAB8B [trans-Golgi network membrane]
RAB8B [cytosol]
Inferred To
GGC-RAB8B [cytosol]
(Dictyostelium discoideum)
GGC-RAB8B [cytosol]
(Gallus gallus)
GGC-RAB8B [cytosol]
(Mus musculus)
GGC-RAB8B [cytosol]
(Rattus norvegicus)
GGC-RAB8B [cytosol]
(Saccharomyces cerevisiae)
GGC-RAB8B [cytosol]
(Schizosaccharomyces pombe)
rab-8 [cytosol]
(Caenorhabditis elegans)
RAB8B [cytosol]
(Bos taurus)
RAB8B [cytosol]
(Canis familiaris)
RAB8B [cytosol]
(Sus scrofa)
rabr-1 [cytosol]
(Caenorhabditis elegans)
Rab8 [cytosol]
(Drosophila melanogaster)
rab8b [cytosol]
(Danio rerio)
rab8b [cytosol]
(Xenopus tropicalis)
Homologues of GGC-RAB8B [cytosol]
(Caenorhabditis elegans)
Homologues of GGC-RAB8B [cytosol]
(Dictyostelium discoideum)
Homologues of GGC-RAB8B [cytosol]
(Schizosaccharomyces pombe)
Modified Residues
Name
S-geranylgeranyl-L-cysteine at 204
Coordinate
204
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Cross References
RefSeq
NP_057614.1
OpenTargets
ENSG00000166128
GeneCards
Q92930
HPA
ENSG00000166128-RAB8B
Ensembl
ENSG00000166128
,
ENST00000321437
,
ENSP00000312734
PRO
Q92930
Pharos - Targets
Q92930
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9UK39 NOCT
1
CCRN4L [nucleoplasm]
(R-HSA-508391)
0.527
2
UniProt:Q96I59 NARS2
1
NARS2 [mitochondrial matrix]
(R-HSA-379585)
0.527
3
UniProt:P24386 CHM
1
CHM [cytosol]
(R-HSA-6801097)
0.527
4
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