Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
GGC-RAB21 [cytosol]
Stable Identifier
R-HSA-8873769
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ras-related protein Rab-21, RAB21_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
RAB geranylgeranylation (Homo sapiens)
RGGT geranylgeranylates RAB proteins (Homo sapiens)
CHMs:GGC-RABs:GDP [cytosol] (Homo sapiens)
GGC-RABs:GDP [cytosol] (Homo sapiens)
GGC-RABs [cytosol] (Homo sapiens)
GGC-RAB21 [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
RAB21 GEFs exchange GTP for GDP on RAB21 (Homo sapiens)
GGC-RAB21:GDP:GDIs,CHMs [cytosol] (Homo sapiens)
GGC-RAB21:GDP [cytosol] (Homo sapiens)
GGC-RAB21 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UL25 RAB21
Gene Names
RAB21, KIAA0118
Chain
initiator methionine:1, chain:2-222, propeptide:223-225
Reference Genes
BioGPS Gene:23011 RAB21
COSMIC (genes):RAB21 RAB21
CTD Gene:23011 RAB21
dbSNP Gene:23011 RAB21
ENSEMBL:ENSG00000080371 RAB21
ENSEMBL:ENSG00000080371.6 RAB21
HGNC:18263 RAB21
KEGG Gene (Homo sapiens):23011 RAB21
Monarch:23011 RAB21
NCBI Gene:23011 RAB21
OMIM:612398 RAB21
UCSC:Q9UL25 RAB21
Reference Transcript
RefSeq:NM_014999.3 RAB21
Other Identifiers
11727505_at
11727506_x_at
16754195
203885_PM_at
203885_at
226268_PM_at
226268_at
23011
239329_PM_at
239329_at
241263_PM_at
241263_at
33326_at
3422270
3422271
3422277
3422279
3422282
3422289
3422290
3422293
3422294
3422295
3422296
3422297
3422298
3422299
3422300
3422301
3422302
3422303
3422305
3422307
3422309
3422311
3422313
3422315
3422317
3422319
59971_at
7957177
81936_at
82594_at
89184_at
92108_at
ADDON000173.hg
ADDON001800.hg
A_21_P0014677
A_23_P128166
A_24_P247749
D42087_at
GE494414
GE521804
GE80021
GO:0000139
GO:0000166
GO:0003824
GO:0003924
GO:0005515
GO:0005525
GO:0005576
GO:0005615
GO:0005768
GO:0005769
GO:0005783
GO:0005789
GO:0005794
GO:0005802
GO:0005829
GO:0005886
GO:0005925
GO:0006886
GO:0007018
GO:0008089
GO:0009898
GO:0010008
GO:0012505
GO:0012506
GO:0015031
GO:0016020
GO:0016192
GO:0016787
GO:0017157
GO:0019003
GO:0023052
GO:0030154
GO:0030516
GO:0030659
GO:0031410
GO:0031901
GO:0032154
GO:0032482
GO:0032580
GO:0042995
GO:0043005
GO:0043226
GO:0045202
GO:0048260
GO:0048856
GO:0050775
GO:0050821
GO:0070062
GO:0098559
GO:1904115
GO:2000643
HMNXSV003015335
HMNXSV003046141
Hs.126605.0.A1_3p_at
Hs.154697.0.A1_3p_at
Hs.167028.0.A1_3p_at
ILMN_1746856
PH_hs_0023002
TC12000627.hg
g7661921_3p_at
Participates
as a component of
GGC-RAB21:GDP [cytosol] (Homo sapiens)
as a candidate of
GGC-RABs [cytosol] (Homo sapiens)
Other forms of this molecule
GGC-RAB21 [early endosome membrane]
RAB21 [cytosol]
Inferred To
rab21 [cytosol]
(Xenopus tropicalis)
GGC-RAB21 [cytosol]
(Bos taurus)
GGC-RAB21 [cytosol]
(Danio rerio)
GGC-RAB21 [cytosol]
(Dictyostelium discoideum)
GGC-RAB21 [cytosol]
(Gallus gallus)
GGC-RAB21 [cytosol]
(Mus musculus)
GGC-RAB21 [cytosol]
(Rattus norvegicus)
Rab21 [cytosol]
(Drosophila melanogaster)
rab-21 [cytosol]
(Caenorhabditis elegans)
Modified Residues
Name
S-geranylgeranyl-L-cysteine at 221
Coordinate
221
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Name
S-geranylgeranyl-L-cysteine at 222
Coordinate
222
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Cross References
RefSeq
NP_055814.1
OpenTargets
ENSG00000080371
GeneCards
Q9UL25
HPA
ENSG00000080371-RAB21
Ensembl
ENST00000261263
,
ENSP00000261263
,
ENSG00000080371
PRO
Q9UL25
Pharos - Targets
Q9UL25
PDB
2OT3
,
1Z0I
,
1YZT
,
1Z08
,
1YZU
© 2023
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text