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About
What is Reactome ?
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Team
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Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
User Guide
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
Data Model
Computational inferred events
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Citing us
Tools
Pathway Browser
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Species Comparison
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RPL36A,RPL36AL
Stable Identifier
R-HSA-8868819
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Axon guidance (Homo sapiens)
Signaling by ROBO receptors (Homo sapiens)
Regulation of expression of SLITs and ROBOs (Homo sapiens)
Translation of ROBO3.2 mRNA initiates NMD (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Translated ROBO3.2 mRNA in complex with NMD-initiating UPF2 [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Translation of ROBO3.2 mRNA is negatively regulated by NMD (Homo sapiens)
Translated ROBO3.2 mRNA in complex with NMD-initiating UPF2 [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Influenza Infection (Homo sapiens)
Influenza Life Cycle (Homo sapiens)
Influenza Viral RNA Transcription and Replication (Homo sapiens)
Viral mRNA Translation (Homo sapiens)
Synthesis of PB1-F2 (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Viral Protein Synthesis (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Selenoamino acid metabolism (Homo sapiens)
Selenocysteine synthesis (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Metabolism of RNA (Homo sapiens)
Nonsense-Mediated Decay (NMD) (Homo sapiens)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Homo sapiens)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Homo sapiens)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
SMG6 hydrolyzes mRNA with premature termination codon (Homo sapiens)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Homo sapiens)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Homo sapiens)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Homo sapiens)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
Eukaryotic Translation Elongation (Homo sapiens)
Peptide chain elongation (Homo sapiens)
Aminoacyl-tRNA binds to the ribosome at the A-site (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
80S:aminoacyl tRNA:mRNA:eEF1A:GTP [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Hydrolysis of eEF1A:GTP (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:aminoacyl-tRNA [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
80S:aminoacyl tRNA:mRNA:eEF1A:GTP [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Peptide transfer from P-site tRNA to the A-site tRNA (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:aminoacyl-tRNA [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Elongation complex with growing peptide chain [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Translocation of ribosome by 3 bases in the 3' direction (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Elongation complex with growing peptide chain [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Eukaryotic Translation Initiation (Homo sapiens)
Cap-dependent Translation Initiation (Homo sapiens)
Formation of a pool of free 40S subunits (Homo sapiens)
Release of 40S and 60S subunits from the 80S ribosome (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
GTP hydrolysis and joining of the 60S ribosomal subunit (Homo sapiens)
The 60S subunit joins the translation initiation complex (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
eIF5B:GTP is hydrolyzed and released (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
L13a-mediated translational silencing of Ceruloplasmin expression (Homo sapiens)
Dissociation of L13a from the 60s ribosomal subunit (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
60s ribosomal complex lacking L13a subunit [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Eukaryotic Translation Termination (Homo sapiens)
GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex (Homo sapiens)
Me-Q185-ETF1 dimer:eRF3:GDP:80S Ribosome:mRNA:peptidyl-tRNA Complex [cytosol] (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Me-Q185-ETF1 dimer:eRF3:GTP:80S Ribosome:mRNA:peptidyl-tRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Me-Q185-ETF1 dimer:eRF3:GTP:80S Ribosome:mRNA:peptidyl-tRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex (Homo sapiens)
Me-Q185-ETF1 dimer:eRF3:GDP:80S Ribosome:mRNA:peptidyl-tRNA Complex [cytosol] (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Me-Q185-ETF1 dimer:eRF3:GDP:80S Ribosome:mRNA:tRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
SRP-dependent cotranslational protein targeting to membrane (Homo sapiens)
Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Homo sapiens)
SRP:polypeptide+signal:ribosome [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein (Homo sapiens)
cleaved polypeptide:Translocon [endoplasmic reticulum membrane] (Homo sapiens)
membrane-bound ribosome:mRNA:cleaved polypeptide [endoplasmic reticulum membrane] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
polypeptide+signal:Translocon [endoplasmic reticulum membrane] (Homo sapiens)
membrane-bound ribosome:mRNA:polypeptide+signal [endoplasmic reticulum membrane] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Signal-containing nascent peptide translocates to endoplasmic reticulum (Homo sapiens)
SRP receptor:SRP:ribosome:polypeptide+signal [endoplasmic reticulum membrane] (Homo sapiens)
SRP:polypeptide+signal:ribosome [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
polypeptide+signal:Translocon [endoplasmic reticulum membrane] (Homo sapiens)
membrane-bound ribosome:mRNA:polypeptide+signal [endoplasmic reticulum membrane] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Synthesis of nascent polypeptide containing signal sequence (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
The SRP receptor binds the SRP:nascent peptide:ribosome complex (Homo sapiens)
SRP receptor:SRP:ribosome:polypeptide+signal [endoplasmic reticulum membrane] (Homo sapiens)
SRP:polypeptide+signal:ribosome [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
SRP:polypeptide+signal:ribosome [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL36A,RPL36AL [cytosol] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
12490704
Functional second genes generated by retrotransposition of the X-linked ribosomal protein genes
Nucleic Acids Res.
2002
19647033
The human large subunit ribosomal protein L36A-like contacts the CCA end of P-site bound tRNA
Biochimie
2009
Participants
members
RPL36A [cytosol] (Homo sapiens)
candidates
RPL36AL [cytosol] (Homo sapiens)
Participant Of
hasComponent
60S ribosomal complex [cytosol]
60s ribosomal complex lacking L13a subunit [cytosol]
Inferred To
Ghost homologue of RPL36A,RPL36AL [cytosol] (Rattus norvegicus)
RPL36A,RPL36AL [cytosol] (Arabidopsis thaliana)
RPL36A,RPL36AL [cytosol] (Caenorhabditis elegans)
RPL36A,RPL36AL [cytosol] (Danio rerio)
RPL36A,RPL36AL [cytosol] (Dictyostelium discoideum)
RPL36A,RPL36AL [cytosol] (Drosophila melanogaster)
RPL36A,RPL36AL [cytosol] (Gallus gallus)
RPL36A,RPL36AL [cytosol] (Mus musculus)
RPL36A,RPL36AL [cytosol] (Oryza sativa)
RPL36A,RPL36AL [cytosol] (Plasmodium falciparum)
RPL36A,RPL36AL [cytosol] (Saccharomyces cerevisiae)
RPL36A,RPL36AL [cytosol] (Schizosaccharomyces pombe)
RPL36A,RPL36AL [cytosol] (Taeniopygia guttata)
RPL36A,RPL36AL [cytosol] (Xenopus tropicalis)
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