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rRNA processing in the mitochondrion
Stable Identifier
R-HSA-8868766
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the mitochondrion (Homo sapiens)
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Mitochondrial ribosomes contain 16S rRNA (large subunit) and 12S rRNA (small subunit) that are encoded in the mitochondrial genome and produced by processing of a long H strand transcript (reviewed in Van Haute et al. 2015). Enzymes encoded in the nucleus and acting in the mitochondrial matrix modify 5 nucleotides in the 12S RNA and 4 nucleotides in the 16S rRNA (reviewed in Van Haute et al. 2015).
Literature References
PubMed ID
Title
Journal
Year
26016801
Mitochondrial transcript maturation and its disorders
Powell, CA
,
Minczuk, M
,
Van Haute, L
,
Nicholls, TJ
,
Pearce, SF
,
D'Souza, AR
J. Inherit. Metab. Dis.
2015
Participants
Events
Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript
(Homo sapiens)
rRNA modification in the mitochondrion
(Homo sapiens)
Participates
as an event of
rRNA processing (Homo sapiens)
Event Information
Go Biological Process
rRNA processing (0006364)
Authored
May, B (2016-04-25)
Reviewed
Bogenhagen, DF (2016-04-25)
Created
May, B (2016-04-25)
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