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DCAF6 [nucleoplasm]
Stable Identifier
R-HSA-8863252
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
DDB1- and CUL4-associated factor 6, DCAF6_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Neddylation (Homo sapiens)
AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Homo sapiens)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Homo sapiens)
DCAF protein [nucleoplasm] (Homo sapiens)
DCAF6 [nucleoplasm] (Homo sapiens)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Homo sapiens)
DCAF protein [nucleoplasm] (Homo sapiens)
DCAF6 [nucleoplasm] (Homo sapiens)
CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Homo sapiens)
CRL4 E3 ubiquitin ligase:CAND1 [nucleoplasm] (Homo sapiens)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Homo sapiens)
DCAF protein [nucleoplasm] (Homo sapiens)
DCAF6 [nucleoplasm] (Homo sapiens)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Homo sapiens)
DCAF protein [nucleoplasm] (Homo sapiens)
DCAF6 [nucleoplasm] (Homo sapiens)
COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Homo sapiens)
CRL4 E3 ubiquitin ligase:CAND1 [nucleoplasm] (Homo sapiens)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Homo sapiens)
DCAF protein [nucleoplasm] (Homo sapiens)
DCAF6 [nucleoplasm] (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Homo sapiens)
DCAF protein [nucleoplasm] (Homo sapiens)
DCAF6 [nucleoplasm] (Homo sapiens)
COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Homo sapiens)
DCAF protein [nucleoplasm] (Homo sapiens)
DCAF6 [nucleoplasm] (Homo sapiens)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Homo sapiens)
DCAF protein [nucleoplasm] (Homo sapiens)
DCAF6 [nucleoplasm] (Homo sapiens)
NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Homo sapiens)
DCAF protein [nucleoplasm] (Homo sapiens)
DCAF6 [nucleoplasm] (Homo sapiens)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Homo sapiens)
DCAF protein [nucleoplasm] (Homo sapiens)
DCAF6 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q58WW2 DCAF6
Gene Names
DCAF6, IQWD1, MSTP055
Chain
chain:1-860
Reference Genes
BioGPS Gene:55827 DCAF6
COSMIC (genes):DCAF6 DCAF6
CTD Gene:55827 DCAF6
dbSNP Gene:55827 DCAF6
ENSEMBL:ENSG00000143164 DCAF6
HGNC:30002 DCAF6
Monarch:55827 DCAF6
NCBI Gene:55827 DCAF6
OMIM:610494 DCAF6
UCSC:Q58WW2 DCAF6
Reference Transcript
RefSeq:NM_001017977.2 DCAF6
RefSeq:NM_001198957.1 DCAF6
RefSeq:NM_018442.3 DCAF6
RefSeq:NM_001198956.1 DCAF6
Other Identifiers
11726428_a_at
11743648_a_at
11743649_a_at
11748416_a_at
11756205_x_at
16673428
217908_PM_s_at
217908_s_at
232349_PM_x_at
232349_x_at
2366029
2366030
2366031
2366032
2366033
2366034
2366040
2366041
2366042
2366043
2366045
2366047
2366049
2366050
2366051
2366052
2366053
2366057
2366058
2366059
2366060
2366061
2366062
2366063
2366066
2366068
2366069
2366070
2366071
2366072
2366073
2366074
2366075
2366076
2366080
2366082
2366083
2366085
2366086
2366087
2366088
2366091
2366094
2366095
2366096
2366097
2366098
2366099
2366101
2366104
2366105
2366106
3615548
3615549
3615551
3615552
55827
65746_at
7907104
A_23_P160481
A_33_P3294449
GE61623
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005925
GO:0006355
GO:0016567
GO:0030374
GO:0043226
GO:0045944
GO:0060090
GO:0080008
GO:0140110
HMNXSV003001617
Hs.279882.1.A1_3p_a_at
Hs.279882.1.A1_3p_x_at
ILMN_1670000
ILMN_1698985
ILMN_2392080
PH_hs_0039958
TC01001463.hg
g8923955_3p_a_at
Participates
as a member of
DCAF protein [nucleoplasm] (Homo sapiens)
Inferred To
Dcaf6 [nucleoplasm]
(Mus musculus)
Dcaf6 [nucleoplasm]
(Rattus norvegicus)
iqw1 [nucleoplasm]
(Schizosaccharomyces pombe)
DCAF6 [nucleoplasm]
(Bos taurus)
DCAF6 [nucleoplasm]
(Canis familiaris)
DCAF6 [nucleoplasm]
(Dictyostelium discoideum)
DCAF6 [nucleoplasm]
(Sus scrofa)
dcaf6 [nucleoplasm]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENSP00000356817
,
ENST00000432587
,
ENSP00000311949
,
ENST00000312263
,
ENSP00000396238
,
ENST00000367843
,
ENST00000367840
,
ENSP00000356814
OpenTargets
ENSG00000143164
HPA
ENSG00000143164-DCAF6
PRO
Q58WW2
Pharos - Targets
Q58WW2
PDB
3I7O
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