CSF3 dimer:CSFR binds CSFR

Stable Identifier
R-HSA-8854738
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
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CSF3 dimer:CSFR binds CSFR
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CSF3R ligand-binding is associated with dimerization of the receptor (Aritomi et al. 1999, Tamada et al. 2006, Layton & Hall 2006) and signal transduction through Jak/STAT, Lyn and Erk1/2.

Literature References
PubMed ID Title Journal Year
16492764 Homodimeric cross-over structure of the human granulocyte colony-stimulating factor (GCSF) receptor signaling complex

Tamada, T, Honjo, E, Maeda, Y, Okamoto, T, Ishibashi, M, Tokunaga, M, Kuroki, R

Proc. Natl. Acad. Sci. U.S.A. 2006
Participants
Input
Output
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as an event of
Orthologous Events
CSF3 dimer:CSFR binds CSFR (Danio rerio)
CSF3 dimer:CSFR binds CSFR (Gallus gallus)
CSF3 dimer:CSFR binds CSFR (Mus musculus)
CSF3 dimer:CSFR binds CSFR (Rattus norvegicus)
CSF3 dimer:CSFR binds CSFR (Sus scrofa)
CSF3 dimer:CSFR binds CSFR (Xenopus tropicalis)
Authored
Jupe, S  (2014-06-04)
Reviewed
Meldal, BH  (2016-01-28)
Created
Jupe, S  (2016-01-28)
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