BTN2A2 binds T cell surface

Stable Identifier
R-HSA-8851988
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
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BTN2A2 binds T cell surface
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BTN2A2 protein is upregulated upon T cell activation and interacts with activated T cells suggesting the presence of one or more receptors on these cells. It has been demonstrated that BTN2A2 inhibits T cell metabolism upon binding to its putative receptor on T cells (Smith et al. 2010).

Literature References
PubMed ID Title Journal Year
20208008 BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation

Smith, IA, Knezevic, BR, Ammann, JU, Rhodes, DA, Aw, D, Palmer, DB, Mather, IH, Trowsdale, J

J. Immunol. 2010
Participants
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Authored
Garapati, P V  (2016-01-05)
Reviewed
Reith, W  (2016-09-09)
Rhodes, DA  (2017-03-01)
Created
Garapati, P V  (2016-01-12)