Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
TRAIP [cytosol]
Stable Identifier
R-HSA-8851652
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase TRAIP ecNumber6.3.2.-/ecNumber, TRAIP_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAIP [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BWF2 TRAIP
Gene Names
TRAIP, RNF206, TRIP
Chain
chain:1-469
Reference Genes
BioGPS Gene:10293 TRAIP
COSMIC (genes):TRAIP TRAIP
CTD Gene:10293 TRAIP
dbSNP Gene:10293 TRAIP
ENSEMBL:ENSG00000183763 TRAIP
HGNC:30764 TRAIP
KEGG Gene (Homo sapiens):10293 TRAIP
Monarch:10293 TRAIP
NCBI Gene:10293 TRAIP
OMIM:605958 TRAIP
UCSC:Q9BWF2 TRAIP
Reference Transcript
RefSeq:NM_005879.2 TRAIP
Other Identifiers
0001090528
10293
11755941_a_at
16954251
205598_at
2674809
2674810
2674813
2674814
2674815
2674816
2674818
2674821
2674823
2674825
2674828
2674829
2674832
2674833
2674835
2674838
2674839
2674840
2674841
38953_at
8087513
A_23_P170491
GE81571
GO:0003674
GO:0004842
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005730
GO:0005737
GO:0006464
GO:0006915
GO:0007165
GO:0008150
GO:0008219
GO:0009058
GO:0010804
GO:0016567
GO:0016740
GO:0032088
GO:0032688
GO:0034641
GO:0042802
GO:0043167
GO:0043226
GO:0046872
GO:0048471
GO:0061630
ILMN_1715540
TC03001419.hg
U77845_at
g5032194_3p_at
Participant Of
hasCandidate
E3 ligases in proteasomal degradation [cytosol]
Inferred To
nopo [cytosol] (Drosophila melanogaster)
TRAIP [cytosol] (Bos taurus)
TRAIP [cytosol] (Canis familiaris)
TRAIP [cytosol] (Gallus gallus)
TRAIP [cytosol] (Sus scrofa)
Traip [cytosol] (Mus musculus)
Traip [cytosol] (Rattus norvegicus)
trul-1 [cytosol] (Caenorhabditis elegans)
traip [cytosol] (Danio rerio)
traip [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
NP_005870.2
OpenTargets
ENSG00000183763
HPA
ENSG00000183763-TRAIP
GeneCards
Q9BWF2
Ensembl
ENSG00000183763
,
ENSP00000328203
,
ENST00000331456
PRO
Q9BWF2
Orphanet
23603
PDB
4ZTD
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O15160 POLR1C
2
POLR1C [nucleoplasm]
(R-HSA-63498)
POLR1C [cytosol]
(R-HSA-1964454)
0.556
3
© 2021
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text