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SALMs 1-4 bind reticulon 3
Stable Identifier
R-HSA-8849882
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
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Neuronal System (Homo sapiens)
Protein-protein interactions at synapses (Homo sapiens)
Synaptic adhesion-like molecules (Homo sapiens)
SALMs 1-4 bind reticulon 3 (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
In the brain, reticulon 3 (RTN3) tightly associates with SALM2 and SALM3 to form a complex, and interacts relatively weakly with SALM1 and SALM4. This interaction is mediated by the LRR domain in SALMs (Chang et al. 2010).
Literature References
PubMed ID
Title
Journal
Year
19681166
Reticulon 3 is an interacting partner of the SALM family of adhesion molecules
Wang, CY
,
Wenthold, RJ
,
Seabold, GK
,
Chang, K
J. Neurosci. Res.
2010
Participants
Input
RTN3 [plasma membrane]
(Homo sapiens)
SALM2,3(SALM1,4) [plasma membrane]
(Homo sapiens)
Output
SALM2,3(SALM1,4):RTN3 [plasma membrane]
(Homo sapiens)
Participates
as an event of
Synaptic adhesion-like molecules (Homo sapiens)
Orthologous Events
SALMs 1-4 bind reticulon 3 (Caenorhabditis elegans)
SALMs 1-4 bind reticulon 3 (Canis familiaris)
SALMs 1-4 bind reticulon 3 (Drosophila melanogaster)
SALMs 1-4 bind reticulon 3 (Mus musculus)
SALMs 1-4 bind reticulon 3 (Rattus norvegicus)
Authored
Garapati, P V (2015-12-18)
Reviewed
Kim, E (2016-02-04)
Petralia, RS (2016-05-17)
Seabold, GK (2016-05-17)
Created
Garapati, P V (2015-12-18)
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