MDP:NLRP1 binds ATP

Stable Identifier
R-HSA-879222
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

MDP may induce a conformational change in NLRP1 which enables ATP binding, required for NLRP1 oligomerization (Faustin et al. 2007).

Literature References
PubMed ID Title Journal Year
17349957 Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

Faustin, B, Lartigue, L, Bruey, JM, Luciano, F, Sergienko, E, Bailly-Maitre, B, Volkmann, N, Hanein, D, Rouiller, I, Reed, JC

Mol Cell 2007
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created