MDP:NLRP1 binds ATP

Stable Identifier
R-HSA-879222
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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MDP:NLRP1 binds ATP
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
MDP may induce a conformational change in NLRP1 which enables ATP binding, required for NLRP1 oligomerization (Faustin et al. 2007).
Literature References
PubMed ID Title Journal Year
17349957 Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

Lartigue, L, Reed, JC, Rouiller, I, Bruey, JM, Faustin, B, Sergienko, E, Volkmann, N, Luciano, F, Bailly-Maitre, B, Hanein, D

Mol Cell 2007
Participants
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Output
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Orthologous Events
MDP:NLRP1 binds ATP (Bos taurus)
MDP:NLRP1 binds ATP (Canis familiaris)
MDP:NLRP1 binds ATP (Danio rerio)
MDP:NLRP1 binds ATP (Gallus gallus)
MDP:NLRP1 binds ATP (Mus musculus)
MDP:NLRP1 binds ATP (Rattus norvegicus)
Authored
Jupe, S  (2010-04-22)
Reviewed
Kufer, TA  (2011-04-28)
Rittinger, K  (2011-06-06)
Wong, E  (2011-06-06)
Created
Jupe, S  (2010-06-15)
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