MDP:NLRP1 binds ATP

Stable Identifier
R-HSA-879222
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
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MDP:NLRP1 binds ATP
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MDP may induce a conformational change in NLRP1 which enables ATP binding, required for NLRP1 oligomerization (Faustin et al. 2007).

Literature References
PubMed ID Title Journal Year
17349957 Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

Faustin, B, Lartigue, L, Bruey, JM, Luciano, F, Sergienko, E, Bailly-Maitre, B, Volkmann, N, Hanein, D, Rouiller, I, Reed, JC

Mol Cell 2007
Participants
Input
Output
Participant Of
hasEvent
Orthologous Events
MDP:NLRP1 binds ATP (Canis familiaris)
MDP:NLRP1 binds ATP (Gallus gallus)
MDP:NLRP1 binds ATP (Mus musculus)
MDP:NLRP1 binds ATP (Rattus norvegicus)
MDP:NLRP1 binds ATP (Sus scrofa)
MDP:NLRP1 binds ATP (Xenopus tropicalis)
Authored
Jupe, S  (2010-04-22)
Reviewed
Kufer, TA  (2011-04-28)
Rittinger, K  (2011-06-06)
Wong, E  (2011-06-06)
Created
Jupe, S  (2010-06-15)
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