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NLRP3:SUGT1:HSP90 [cytosol]
Stable Identifier
R-HSA-874086
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Leishmania infection (Homo sapiens)
Cell recruitment (pro-inflammatory response) (Homo sapiens)
Purinergic signaling in leishmaniasis infection (Homo sapiens)
ASC is recruited via a PYD-PYD interaction (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 [cytosol] (Homo sapiens)
NLRP3 elicitor proteins:NLRP3 [cytosol] (Homo sapiens)
NLRP3:SUGT1:HSP90 [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer:ASC [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 [cytosol] (Homo sapiens)
NLRP3 elicitor proteins:NLRP3 [cytosol] (Homo sapiens)
NLRP3:SUGT1:HSP90 [cytosol] (Homo sapiens)
NLRP3 activation by small molecules (Homo sapiens)
NLRP3:SUGT1:HSP90 [cytosol] (Homo sapiens)
SGT1:HSP90 binds inactive NLRP3 (Homo sapiens)
NLRP3:SUGT1:HSP90 [cytosol] (Homo sapiens)
The CARD domain of ASC recruits Procaspase-1 (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer:ASC [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 [cytosol] (Homo sapiens)
NLRP3 elicitor proteins:NLRP3 [cytosol] (Homo sapiens)
NLRP3:SUGT1:HSP90 [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer:ASC:Procaspase-1 [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer:ASC [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 [cytosol] (Homo sapiens)
NLRP3 elicitor proteins:NLRP3 [cytosol] (Homo sapiens)
NLRP3:SUGT1:HSP90 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Homo sapiens)
Inflammasomes (Homo sapiens)
The NLRP3 inflammasome (Homo sapiens)
ASC is recruited via a PYD-PYD interaction (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 [cytosol] (Homo sapiens)
NLRP3 elicitor proteins:NLRP3 [cytosol] (Homo sapiens)
NLRP3:SUGT1:HSP90 [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer:ASC [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 [cytosol] (Homo sapiens)
NLRP3 elicitor proteins:NLRP3 [cytosol] (Homo sapiens)
NLRP3:SUGT1:HSP90 [cytosol] (Homo sapiens)
NLRP3 activation by elicitor proteins (Homo sapiens)
NLRP3 elicitor proteins:NLRP3 [cytosol] (Homo sapiens)
NLRP3:SUGT1:HSP90 [cytosol] (Homo sapiens)
NLRP3:SUGT1:HSP90 [cytosol] (Homo sapiens)
NLRP3 activation by small molecules (Homo sapiens)
NLRP3:SUGT1:HSP90 [cytosol] (Homo sapiens)
NLRP3 oligomerizes via NACHT domains (Homo sapiens)
NLRP3 elicitors:NLRP3 [cytosol] (Homo sapiens)
NLRP3 elicitor proteins:NLRP3 [cytosol] (Homo sapiens)
NLRP3:SUGT1:HSP90 [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 [cytosol] (Homo sapiens)
NLRP3 elicitor proteins:NLRP3 [cytosol] (Homo sapiens)
NLRP3:SUGT1:HSP90 [cytosol] (Homo sapiens)
SGT1:HSP90 binds inactive NLRP3 (Homo sapiens)
NLRP3:SUGT1:HSP90 [cytosol] (Homo sapiens)
The CARD domain of ASC recruits Procaspase-1 (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer:ASC [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 [cytosol] (Homo sapiens)
NLRP3 elicitor proteins:NLRP3 [cytosol] (Homo sapiens)
NLRP3:SUGT1:HSP90 [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer:ASC:Procaspase-1 [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer:ASC [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 oligomer [cytosol] (Homo sapiens)
NLRP3 elicitors:NLRP3 [cytosol] (Homo sapiens)
NLRP3 elicitor proteins:NLRP3 [cytosol] (Homo sapiens)
NLRP3:SUGT1:HSP90 [cytosol] (Homo sapiens)
Participants
components
NLRP3 [cytosol] (Homo sapiens)
SUGT1:HSP90 [cytosol] (Homo sapiens)
Participant Of
input
NLRP3 activation by elicitor proteins
NLRP3 activation by small molecules
output
SGT1:HSP90 binds inactive NLRP3
hasComponent
NLRP3 elicitor proteins:NLRP3 [cytosol]
Inferred To
NLRP3:SUGT1:HSP90 [cytosol] (Canis familiaris)
NLRP3:SUGT1:HSP90 [cytosol] (Danio rerio)
NLRP3:SUGT1:HSP90 [cytosol] (Mus musculus)
NLRP3:SUGT1:HSP90 [cytosol] (Rattus norvegicus)
NLRP3:SUGT1:HSP90 [cytosol] (Sus scrofa)
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